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Maternal experience of fetal movements from a child with AMC: MECA survey

2025· article· en· W4410935787 on OpenAlexaff
Arda Arduç, Ingeborg H. Linskens, Chakravarthy U. Dussa, Harold J. P. van Bosse, Sara Lemin, Bonita Sawatzky, Isabel Filges, Johanna I.P. de Vries

Bibliographic record

VenueEarly Human Development · 2025
Typearticle
Languageen
FieldMedicine
TopicNeurogenetic and Muscular Disorders Research
Canadian institutionsUniversity of British Columbia
FundersAcademisch Medisch CentrumAmsterdam University Medical Centers
KeywordsFetal movementPregnancyFetusMedicinePerceptionObstetricsPsychologyArthrogryposis multiplex congenitaDevelopmental psychologyArthrogryposisSurgeryBiology

Abstract

fetched live from OpenAlex

OBJECTIVE: The prevailing assumption is that fetal movements are always absent or reduced in pregnancies affected by arthrogryposis multiplex congenita (AMC), leading to the belief that mothers do not perceive or perceive less fetal movements during affected pregnancies. This study aims to investigate the maternal perception of fetal movements in pregnancies with a child diagnosed with AMC and to challenge this assumption. Additionally, it seeks to expand current knowledge on the perception by comparing with pregnancies with children not affected by AMC. METHODS: A survey-based study was conducted in collaboration with international patient support groups. The survey included mothers with at least one child diagnosed with AMC. The questionnaire covered not only the presence of movements, but also other aspects such as daily movements, consistency throughout the pregnancy, and perceived normalcy. A subgroup comparison was made between mothers who had both an affected and non-affected pregnancy, as well as by pregnancy order and its impact on clinical follow-up. RESULTS: A total of 170 mothers participated in this survey and 118 (70 %) of them had both an affected and non-affected pregnancy and 52 (30 %) had pregnancies with AMC-affected children alone. Most (77 %) perceived fetal movements during AMC-affected pregnancies, though fewer described them as daily (66 %), stable (51 %), or normal (44 %) compared to unaffected pregnancies. CONCLUSION: This study showed that fetal movements can be perceived by the majority of mothers of children with AMC. The presence of fetal movements should not rule out the possibility of AMC in case of fetal contractures.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.298
Teacher spread0.278 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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