The Differences in Western Ontario Rotator Cuff Scores and Transforming Growth Factor-Β Levels Between the use of Platelet Rich Plasma Therapy and Non-Platelet Rich Plasma Therapy in the Conservative Management of Patients with Partial Rotator Cuff Injury
Bibliographic record
Abstract
Introduction: Partial rotator cuff injuries are a major cause of shoulder pain and significant functional impairment. Conservative therapy with physiotherapy and steroid injections is commonly used but has limitations in long-term effectiveness. Platelet Rich Plasma (PRP) has emerged as an alternative therapy with the potential to accelerate healing through regenerative and anti-inflammatory mechanisms. However, the effectiveness of PRP in improving shoulder function and Transforming Growth Factor-β (TGF-β) levels in patients with partial rotator cuff injuries still needs further investigation. This study aims to determine the differences in the Western Ontario Rotator Cuff Index (WORC) score and TGF-β levels in patients with partial rotator cuff injuries who receive conservative physiotherapy with and without PRP injections. Material & Methods: This study is an observational analytic study with a prospective cohort design. Data were obtained from the medical records of patients with partial rotator cuff injuries who underwent conservative therapy with or without PRP injections. WORC scores and TGF-β levels were measured before therapy and three months after treatment. Statistical analysis was performed to evaluate differences between the two groups. Results: The study results indicate a more significant decrease in WORC scores in the group receiving PRP injections compared to the physiotherapy group without PRP. Additionally, TGF-β levels increased more in the PRP group than in the conservative therapy group, suggesting a better regenerative effect than standard conservative therapy. Conclusion: The administration of PRP injections in patients with partial rotator cuff injuries yields better outcomes in reducing WORC scores and increasing TGF-β levels compared to conservative physiotherapy. These findings support the potential of PRP as an adjunct therapy in the conservative management of partial rotator cuff injuries. Keywords: Conservative Therapy, Partial Rotator Cuff, Platelet Rich Plasma, Transforming Growth Factor-β, Western Ontario Rotator Cuff Index
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".