MétaCan
Menu
Back to cohort
Record W4411070664 · doi:10.1638/2024-0092

PERIOPERATIVE ANALGESIC MANAGEMENT IN ASIATIC BLACK BEARS (URSUS THIBETANUS) UNDERGOING OPEN CHOLECYSTECTOMY

2025· article· en· W4411070664 on OpenAlexaff
Szilvia K. Kalogeropoulu, Johanna Painer‐Gigler, Inga‐Catalina Cruz Benedetti, Irene Redtenbacher, Bonnie L. Raphael, Friederike Pohlin, Natalí Verdier

Bibliographic record

VenueJournal of Zoo and Wildlife Medicine · 2025
Typearticle
Languageen
FieldVeterinary
TopicVeterinary Pharmacology and Anesthesia
Canadian institutionsUniversité de MontréalCegep de Saint Hyacinthe
Fundersnot available
KeywordsAnalgesicOpen cholecystectomyMedicinePerioperativeCholecystectomyAnesthesiaSurgery

Abstract

fetched live from OpenAlex

) rescued from bile farms in Vietnam were diagnosed with chronic cholecystitis that required surgical intervention. In addition, these bears exhibited various comorbidities, including cardiovascular changes, chronic kidney disease, degenerative joint disease, obesity, and sarcopenia. The bears were anesthetized for an open midline cholecystectomy using a combination of 3 mg/kg tiletamine/zolazepam, 0.035 mg/kg medetomidine, and 0.05 mg/kg butorphanol administered IM via blowpipe. Anesthesia was maintained with isoflurane in 100% oxygen. Butorphanol IV was repeated q90 min, and meloxicam was given SC at the beginning of surgery. An ultrasound-guided one-point transversus abdominis plane (TAP) block with 0.25% bupivacaine (0.2 ml/kg) was performed in order to desensitize the ventral branches of the last thoracic and lumbar spinal nerves, which innervate the abdominal wall. Additionally, 0.1 ml/kg of same injectate was instilled intraperitoneally twice to manage visceral pain. Lidocaine was administered IV as a continuous-rate infusion at a rate of 10 µg/kg/min. Throughout the procedure, all bears received intravenous fluids and systemic antibiotics. In all bears, cardiovascular parameters remained stable during surgery: heart rate 56 ± 9 bpm, respiratory rate 8 ± 3 bpm and mean arterial blood pressure 128 ± 40 mmHg. No cardiovascular response to surgical stimuli was observed. The TAP block was easy to perform, and no complications were observed during or after the block. The overall dose of local anesthetics was maintained within the recommended range for carnivores, with no signs of local anesthetic toxicity observed. All animals recovered well from anesthesia and returned to their husbandry routine within 6 wk postcholecystectomy. This multimodal analgesic approach seemed to have been effective to provide perioperative analgesia in these Asiatic black bears. It was demonstrated to be a safe, cost-effective, and easily implemented protocol.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.047
GPT teacher head0.374
Teacher spread0.327 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueJournal of Zoo and Wildlife MedicineSame topicVeterinary Pharmacology and AnesthesiaFrench-language works237,207