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Record W4411134330 · doi:10.1002/clt2.70071

Associations with food allergy‐related psychological distress in a global sample of adults, children and caregivers

2025· article· en· W4411134330 on OpenAlexafffundabout
Simon Purser, Christina Jones, Jennifer L. P. Protudjer, Linda Herbert, Cassandra Screti, Caity Roleston, Emily Mattacola, Helen A. Brough, C. Warren, Laura Polloni, Alexandra F. Santos, Ruchi S. Gupta, Mary Jane Marchisotto, Rebecca Knibb

Bibliographic record

VenueClinical and Translational Allergy · 2025
Typearticle
Languageen
FieldMedicine
TopicFood Allergy and Anaphylaxis Research
Canadian institutionsUniversity of ManitobaChildren's Hospital Research Institute of Manitoba
FundersEuropean Academy of Allergy and Clinical ImmunologyNational Peanut BoardNational Institute of Allergy and Infectious DiseasesFood Allergy CanadaAimmune TherapeuticsNovartis
KeywordsMedicineDistressMedical prescriptionAnxietyResidenceClinical psychologyMental healthPsychiatryQuality of life (healthcare)DemographyNursing

Abstract

fetched live from OpenAlex

OBJECTIVE: Food allergy (FA) impacts health-related quality of life and mental health. Understanding what variables are associated with psychological distress can help healthcare providers direct patients to appropriate support. As part of the study, Global Access to Psychological Services (GAPS) for FA and associations with FA-related psychological distress were explored in adults with FA and caregivers of children with FA. METHODS: Participants completed online surveys in seven languages. Participants reported the types of FA-related distress they or their child experienced, along with demographic and FA-related information. Associations with distress were analysed using regression models. RESULTS: N = 1329 adults with FA and N = 1373 caregivers of children with FA from 27 countries participated. Of the 21 different types of distress selected, anxiety about an allergic reaction was the most common (62.5% adults; 72.6% caregivers). Females reported significantly more types of distress than males (p < 0.001). There were significant differences between countries (all p < 0.05-0.001); participants in Australia, Brazil, Canada, and the United Kingdom consistently reported more types of distress than European countries or the United States. In regression models, country of residence, number of FAs, and symptoms were significantly associated with distress. Additional associations included adrenaline autoinjector (AAI) prescription, being female, anaphylaxis and comorbidities in adults; in caregivers having a younger child, longer time elapsed since FA diagnosis, being female, AAI prescription and anaphylaxis; and in children being older and living longer with FA. CONCLUSIONS: FA-related distress is experienced differently across countries. Understanding associations with types of distress can help direct healthcare services and psychological support to where it is needed most.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.097
Threshold uncertainty score0.338

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.344
Teacher spread0.321 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes3
Has abstractyes

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