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Record W4411170303 · doi:10.1097/qai.0000000000003701

Brief Report: Pathways From Childhood Abuse History to Adulthood Mental Health Among Women Living With HIV in Canada: Longitudinal Cohort Findings

2025· article· en· W4411170303 on OpenAlexafffundabout
Carmen H. Logie, Nina Sokolovic, V. Logan Kennedy, Angela Underhill, Claudette Cardinal, Angela Kaida, Alexandra de Pokomandy, Mona Loutfy

Bibliographic record

VenueJAIDS Journal of Acquired Immune Deficiency Syndromes · 2025
Typearticle
Languageen
FieldPsychology
TopicChild Abuse and Trauma
Canadian institutionsMcGill UniversityMcGill University Health CentreSimon Fraser UniversityAIDS VancouverWomen's College HospitalUniversity of Toronto
FundersCanadian HIV Trials Network, Canadian Institutes of Health ResearchCanada Research ChairsHIV/AIDS and STBBI Research InitiativeOntario HIV Treatment Network
KeywordsMental healthCohortHuman immunodeficiency virus (HIV)Longitudinal studyPsychiatryCohort studyHistory of childhoodPsychologyMedicineLife course approachChildhood abuseGerontologyClinical psychologyDevelopmental psychologySexual abuseDemographySuicide preventionEnvironmental healthPoison controlSociologyFamily medicine

Abstract

fetched live from OpenAlex

INTRODUCTION: Experiencing childhood abuse elevates risks for long-term mental health challenges (MHC); this complex relationship is underexplored among women with HIV. Informed by the 'chains of risk' life-course approach, we examined pathways from childhood abuse to mental health among women with HIV. METHODS: Using longitudinal data from the Canadian HIV Women's Sexual & Reproductive Health Cohort Study [CHIWOS], we examined associations between childhood abuse history (sexual, physical, verbal) and current poverty (income, food insecurity, housing insecurity) at time 1 (T1, August 2013-May 2015), substance use and past 3-month violence at time 2 (T2, June 2015-January 2017), and MHC (depression, PTSD, mental functioning) at time 3 (T3, February 2017-December 2018). We conducted path analysis to examine direct and indirect effects from childhood abuse to adult MHC via poverty, substance abuse, and violence. FINDINGS: Most (68%) participants with reported data (n=1,315) experienced childhood abuse. Childhood abuse was associated with adulthood poverty, violence, substance use, and MHC. T1 poverty was associated with T2 substance use and violence, and T3 MHC. Violence was associated with T3 MHC. The total standardized effect of childhood abuse on T3 MHC was 0.27 ( p <0.001). Half of this effect was indirect (β=0.13, p <0.001), with poverty accounting for 43% of the total indirect effect (β=0.06, p =0.003). CONCLUSIONS: Among women with HIV in Canada, childhood abuse was associated with poorer adulthood mental health; this association was mediated by poverty, violence, and substance use in adulthood. Findings emphasize the need for life-course approaches in women-centred violence and trauma-aware HIV care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.023
Threshold uncertainty score0.167

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.006
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0020.005
Science and technology studies0.0050.001
Scholarly communication0.0020.001
Open science0.0020.003
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.230
Teacher spread0.220 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

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