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Record W4411198916 · doi:10.15232/aas.2024-02671

Effects of supplementing Bacillus subtilis PB6 on health outcomes, Salmonella spp. prevalence, growth performance, and carcass characteristics in finishing beef cattle

2025· article· en· W4411198916 on OpenAlexfundno aff
Ashlee Noelle Hanratty, Kristin E Hales, Colten W Dornbach, Nicole C Burdick Sanchez, Alyssa B Word, Ben P Holland, C Maxwell, Jerilyn Hergenreder, Landon Canterbury, John Tyler Leonhard, J.L.M. Vasconcelos, Doug LaFleur, S Trojan, M. L. Galyean, Paul R. Broadway

Bibliographic record

VenueApplied Animal Science · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicAnimal Nutrition and Physiology
Canadian institutionsnot available
FundersFaculty of Arts and Social Sciences, Carleton UniversityU.S. Department of Agriculture
KeywordsBacillus subtilisSalmonellaBiologyBeef cattleBiotechnologyVeterinary medicineFood scienceAnimal scienceBacteriaMedicineGenetics

Abstract

fetched live from OpenAlex

ABSTRACT Objective We evaluated the effects of supplementation with Bacillus subtilis PB6 on health outcomes, growth performance, fecal Salmonella prevalence, and carcass characteristics in finishing beef steers supplemented the first 60 d or the entire 224 d of the feeding period with B. subtilis PB6. Materials and Methods Crossbred beef steers (n = 3,150; arrival BW 274 ± 30.6 kg) were used in a randomized complete block design consisting of 3 dietary treatments (n = 15 blocks per treatment). Treatments included the following: (1) a control diet contained no B. subtilis PB6 (CON); (2) a diet that included CLOSTAT supplemented with 0.5 g/steer daily of B. subtilis PB6 (CLOSTAT 500, Kemin Industries Inc.) to provide 6.6 × 10 9 cfu/g active ingredient for the entire duration of the feeding period (CLO); or (3) a diet that included B. subtilis PB6 at a dose of 0.5 g/steer daily the initial 60 d of the feeding period (CLO60). Based on established criteria, metaphylaxis was administered after arrival to 7 blocks (21 pens) to prevent bovine respiratory disease. Fresh fecal matter was collected aseptically from multiple locations (n = 10 locations within each pen), and lymph nodes were obtained at slaughter from a subset of carcasses within each lot (n = 12) to determine Salmonella prevalence. Results and Discussion No interactions were observed between treatment and metaphylaxis throughout the study. The percentage of respiratory deaths was greater for steers in CLO60 than CLO and CON from d 0 to 60, but there were no growth performance differences noted among treatments. Likewise, there were no differences in lymph node prevalence of Salmonella among treatments; however, there was a decrease in fecal Salmonella prevalence for CON versus CLO and CLO60 steers from d 45 to 90. Implications and Applications Supplementation of B. subtilis PB6 for the first 60 d or the entire feeding period had no effect on health outcomes, growth performance, and carcass characteristics. Moreover, feeding B. subtilis PB6 for the first 60 d or entire feeding period did not affect Salmonella prevalence in the subiliac lymph nodes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.707
Threshold uncertainty score0.271

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.235
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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