Detecção de Cromossomos em Metáfases: Um Novo Dataset e Estudo de Caso com YOLOv11
Bibliographic record
Abstract
Apesar dos avanços na detecção automática de cromossomos, a maioria dos estudos existentes utiliza bases de dados privadas, o que limita a comparação direta de desempenho entre diferentes métodos. Para preencher essa lacuna, este trabalho desenvolve um novo conjunto de dados composto por 519 imagens de células em metáfase com localização anotada dos cromossomos, utilizando amostras coletadas no Centro Regional de Ciências Nucleares do Nordeste (CRCN-NE). Além disso, são avaliadas três variantes do YOLOv11 (YOLOv11n, YOLOv11s e YOLOv11m), utilizando as métricas Mean Average Precision (mAP), Precision e Recall. Os resultados mostram que o YOLOv11m, com imagens de 1024×1024 pixels, obteve o melhor desempenho, alcançando mAP@50 de 99,24% e mAP@50-95 de 74,86%. Esses resultados destacam o potencial do YOLOv11 na automação da detecção de cromossomos, proporcionando maior precisão e agilidade na análise citogenética. A base de dados está disponível em https://doi.org/10.5281/zenodo.15101359.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.004 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.002 |
| Bibliometrics | 0.004 | 0.002 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.002 | 0.002 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.003 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".