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Record W4411219718 · doi:10.1136/jnis-2025-023345

Recommendations from the International Paediatric Stroke Organization on pediatric neurointerventional best practices based on Delphi consensus

2025· article· en· W4411219718 on OpenAlexaff
Kartik Bhatia, Carmen Parra‐Farinas, Kathleen Colao, Darren B. Orbach, Todd Abruzzo, Adam Rennie, Peter B. Sporns, Adam A. Dmytriw, Heather J. Fullerton, Prakash Muthusami

Bibliographic record

VenueJournal of NeuroInterventional Surgery · 2025
Typearticle
Languageen
FieldMedicine
TopicTraumatic Brain Injury and Neurovascular Disturbances
Canadian institutionsHospital for Sick Children
Fundersnot available
KeywordsMedicinePediatric strokeStroke (engine)DelphiDelphi methodConsensus conferenceMedical emergencyIschemic strokeInternal medicine

Abstract

fetched live from OpenAlex

Paediatric neurointervention (PNI) markedly differs from adult neuro-intervention, requiring highly subspecialized clinical skills, knowledge, and techniques. Minimum standards of practice are well established in adult neurointervention but are lacking in the field of PNI. We sought to develop expert consensus on best practices for neurointervention in children.Using a two-stage Delphi consensus model we sought expert opinions from PNI practitioners worldwide regarding best practices. A two-stage online de-identified survey of PNI practitioners was undertaken assessing opinions on a range of topics including minimum recommended caseloads for PNI centres. Minimum agreement rates of >60% were set to determine consensus on any specific question. Consensus opinions on best practices were reviewed by the International Paediatric Stroke Organization Executive Committee.For the first-stage survey there were n=50 responses and for the second-stage n=45 responses, with practitioners from all inhabited continents represented. Consensus-based best practices included: i) Elective endovascular therapeutic neuro-interventions should be performed in high-volume paediatric centres with an established multi-disciplinary paediatric neurovascular team, and ii) High-volume centres are those that undertake at least 20 paediatric endovascular therapeutic neuro-interventions annually. Paediatric thrombectomy in large-vessel occlusion stroke, an area of increasing interest and attention, poses unique time-sensitive multidisciplinary logistical challenges meriting a dedicated analysis, and as such is not within the purview of this report.Best practices for PNI reported here have been identified through expert consensus and are designed to enhance patient safety whilst providing appropriate clinical access to life-saving procedures.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.008
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.425
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.008
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.070
GPT teacher head0.327
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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Same venueJournal of NeuroInterventional SurgerySame topicTraumatic Brain Injury and Neurovascular DisturbancesFrench-language works237,207