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Record W4411242477 · doi:10.18192/osurj.v4i1.7311

Neurobiological Delusions: Regional Cerebral Blood Flow insights into Cotard’s Syndrome and Schizophrenia

2025· article· en· W4411242477 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
venuePublished in a venue whose home country is Canada.

Bibliographic record

VenueUniversity of Ottawa Science Undergraduate Research Journal · 2025
Typearticle
Languageen
FieldNeuroscience
TopicSpatial Neglect and Hemispheric Dysfunction
Canadian institutionsUniversity of Ottawa
Fundersnot available
KeywordsCerebral blood flowSchizophrenia (object-oriented programming)NeurosciencePsychologyMedicinePsychiatryCardiology

Abstract

fetched live from OpenAlex

Cotard’s syndrome is a clinically rare condition that is characterized by nihilistic or immortality delusions, which are often accompanied by thoughts of suicide, depression, and anxiety. These symptoms vary among individuals but are generally distinguished as a neuropsychiatric disorder. The cause of this condition is further investigated in a recent case study, where a 52-year-old male patient diagnosed with schizophrenia and mild intellectual disability is examined. The patient suffered from several lumbar fractures due to an attempted suicide, and after admission to the hospital, the patient was diagnosed with Cotard’s syndrome. This study aimed to assess the longitudinal changes of regional cerebral blood flow (rCBF) on a single-photon emission computed tomography (SPECT) scan, with respect to a schizophrenic patient displaying Cotard’s syndrome. The symptoms of Cotard’s syndrome appear to dissipate through administration of Lurasidone, which is observed through SPECT and changes in rCBF. The observed correlation between the development of Cotard’s syndrome and an increased rCBF provides a strong basis on the nature of the condition, and enhanced understanding of neuropsychiatric conditions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesScience and technology studies
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.772
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0030.004
Scholarly communication0.0000.001
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.285
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it