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Record W4411275135 · doi:10.1016/j.joen.2025.06.004

Pulpal Deterioration Following Restorative Procedures: A Case – Control Study

2025· article· en· W4411275135 on OpenAlexafffund
A. D. Tepperman, A Ben Suleiman, Gevik Malkhassian, David Chvartszaid, Jim Yuan Lai, Amir Azarpazhooh

Bibliographic record

VenueJournal of Endodontics · 2025
Typearticle
Languageen
FieldDentistry
TopicEndodontics and Root Canal Treatments
Canadian institutionsMount Sinai HospitalBaycrest HospitalUniversity of British ColumbiaUniversity of Toronto
FundersUniversity of TorontoAmerican Association of Endodontists Foundation
KeywordsDentistryRestorative dentistryMedicineOrthodontics

Abstract

fetched live from OpenAlex

INTRODUCTION: While restorative procedures aim to preserve tooth structure and function, they may contribute to pulpal deterioration, potentially necessitating endodontic intervention. This matched case-control study examined the time lapse from the most recent definitive (terminal) restoration to the onset of pulpal deterioration. METHODS: A computerized search of dental records (1999-2023) at the University of Toronto identified 1,360 permanent teeth that received terminal restorations followed by endodontic therapy (cases), matched 1:1 with 1,360 teeth that received terminal restorations without subsequent endodontic therapy (controls). Matching criteria included age at the time of restoration, tooth type, and number of prior restorations. Data were analyzed using descriptive statistics, chi-square tests, and multivariable Cox regression. RESULTS: The median time lapse to pulpal deterioration among cases was 14.3 months. Crowns and bridge retainers had the longest interval (28 months), followed by amalgam (17.4), composite resin (11.9), and glass ionomer (11.4). Earlier deterioration was observed in teeth with restorations involving more than two surfaces (11.5), with more than 2 prior restorations (13.9), and with pulp exposure (6.6). In adjusted analyses, glass ionomer (hazard ratio = 1.6; 95% confidence interval: 1.2-2.2) and multisurface restorations (hazard ratio = 1.5; 95% confidence interval: 1.2-1.7) were statistically significant associated variables. CONCLUSIONS: Pulpal deterioration may occur after a median time lapse of 14.3 months following terminal restoration placement. Crowns/bridge retainers and amalgam restorations were associated with slower progression of pulpal deterioration, whereas composite resin, glass ionomer, multisurface restorations, and pulp exposure were linked to an increased likelihood or earlier onset of pulpal deterioration.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0030.001
Science and technology studies0.0020.003
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.332
Teacher spread0.313 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractno

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