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Record W4411276997 · doi:10.1016/j.joen.2025.06.005

Evaluating Outcomes and Prognostic Factors in Endodontic Microsurgery: A Retrospective Cohort Study

2025· article· en· W4411276997 on OpenAlexaff
C Sperou, A. D. Tepperman, A Ben Suleiman, Gevik Malkhassian, Prakesh S. Shah, Amir Azarpazhooh

Bibliographic record

VenueJournal of Endodontics · 2025
Typearticle
Languageen
FieldDentistry
TopicEndodontics and Root Canal Treatments
Canadian institutionsMount Sinai HospitalUniversity of Toronto
FundersAmerican Association of Endodontists Foundation
KeywordsRetrospective cohort studyMicrosurgeryMedicineDentistryCohortCohort studyGeneral surgerySurgeryInternal medicine

Abstract

fetched live from OpenAlex

INTRODUCTION: Outcome studies are essential for evidence-based endodontics. This study evaluates rates of radiographic periapical healing and survival to reintervention in endodontic microsurgery (EMS), along with the prognostic factors associated with these outcomes. METHODS: Dental records were reviewed to identify teeth treated with EMS at the University of Toronto between 1999 and 2021. Each tooth was tracked until the final follow-up (minimum of 1 year) or an untoward event. Radiographic periapical healing, survival, and their prognostic factors were analyzed using logistic and Cox regression, respectively. Median (interquartile range [IQR]), odds ratios (ORs), hazard ratios (HRs), and 95% confidence intervals (CIs) were calculated (P < .05). RESULTS: A total of 128 teeth met the criteria for radiographic periapical healing analysis, and 186 teeth were included in the survival analysis. The median follow-up time for radiographic periapical healing was 41.5 months (IQR: 27.8-72.9). At the latest follow-up, the overall radiographic periapical healing rate was 82.8%, and it was significantly associated with the absence of periodontal involvement (OR: 2.8, 95% CI: 1.1-7.7, P = .045) and root-end filling depth >2 mm (OR: 3.5, 95% CI: 1.2-9.6, P = .014). Median survival follow-up time was 37.5 months (IQR: 22.3-61.6); 86.6% of teeth survived without reintervention, 1.6% required treatment, and 11.8% were extracted. Age ≤45 (HR: 3.0, P = .036) and root-end filling ≤2 mm (HR: 4.3, P = .004) increased the risk of intervention. CONCLUSIONS: Both radiographic periapical healing and survival rates following EMS are high. Prognostic factors were identified, which require confirmation in future studies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.367
Teacher spread0.331 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractno

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