MétaCan
Menu
Back to cohort

The Effect Of Pentoxifylline On Blood Biomarkers In Patients With Cerebral Infarction Combined With Senile Debilitating Syndrome: Implications For Prognosis

2025· article· en· W4411280622 on OpenAlexaboutno aff
Zhengyuan Lu, Jingping Cheng, Ni Luo

Bibliographic record

VenuePakistan Journal of Pharmaceutical Sciences · 2025
Typearticle
Languageen
FieldMedicine
TopicAcute Ischemic Stroke Management
Canadian institutionsnot available
Fundersnot available
KeywordsPentoxifyllineMedicineCerebral infarctionInternal medicineCardiologyIschemia

Abstract

fetched live from OpenAlex

Cerebral infarction combined with senile debilitating syndrome seriously affects the quality of life of patients, this study analyzed the effect of pentoxifylline on the expression of blood biomarkers in patients with this disease and its relationship with prognosis. 100 patients with cerebral infarction combined with senile debilitating syndrome admitted to our hospital from December 2022 to December 2024 were divided into control and study groups, both groups were treated with basic therapy, and study group were additionally treated with pentoxifylline. The neurological deficit degree (NIHSS score) and Montreal Cognitive Assessment (MoCA) score, coagulation function indicators, blood rheology indicators, inflammatory indicators, clinical efficacy and adverse reactions were analyzed. The relationship of blood biomarker expression with prognosis was assessed using logistic regression analysis and receiver operating characteristic (ROC) curve. After treatment, all indicators in both groups were superior to the pre-treatment (P<0.05). NIHSS score, haematological indicators, inflammatory indicators and adverse reaction incidences of study group were below to control group, MoCA score, coagulation function indexes and clinical efficacy were above to control group (P<0.05). Logistic regression and ROC results showed the effect of blood biomarker expression and prognosis were remarkably correlated. The treatment is efficacious and worthy of clinical promotion.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.049
Threshold uncertainty score0.215

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.351
Teacher spread0.337 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venuePakistan Journal of Pharmaceutical SciencesSame topicAcute Ischemic Stroke ManagementFrench-language works237,207