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Record W4411299567 · doi:10.1093/braincomms/fcaf238

Corticomuscular coherence during upright standing in unilateral transfemoral amputees

2025· article· en· W4411299567 on OpenAlexaff
Britta Meyer, Thomas Krauskopf, Katharina Fuchs, Marvin L. Beusterien, Lukas Klein, Marc Mueller, Tonio Ball, Georg W. Herget, Natalie Mrachacz‐Kersting, Vinzenz von Tscharner, Carsten Mehring, Thomas Stieglitz, Cristian Pasluosta

Bibliographic record

VenueBrain Communications · 2025
Typearticle
Languageen
FieldEngineering
TopicMuscle activation and electromyography studies
Canadian institutionsUniversity of Calgary
FundersBrainLinks-BrainToolsBundesministerium für Bildung und ForschungDeutsche Forschungsgemeinschaft
KeywordsPhysical medicine and rehabilitationPsychologyCoherence (philosophical gambling strategy)MedicineMathematicsStatistics

Abstract

fetched live from OpenAlex

Patients with a lower limb amputation suffer from an impaired balance control and thereby are at a higher risk to fall. To cope with this deficit, they adapt their neuromuscular system by modifying biomechanical and neuromuscular structures. In this study, we investigated changes in corticomuscular coherence between the motor cortex and muscles of the trunk and the intact lower leg. We recorded electroencephalogram (EEG) and electromyogram (EMG) data from 10 unilateral transfemoral amputees and 10 age-matched able-bodied controls during quiet upright stance with eyes open, eyes closed and during dual tasking. To analyse afferent and efferent corticomuscular coherence, directional wavelet coherence between EEG and EMG signals was computed. The corticomuscular coherence analysis showed significant differences between amputees and controls in the afferent and efferent direction and across visual conditions, suggesting differences in the processing of sensory feedback. A power spectral density analysis of the motor cortex contralateral to the amputated leg of amputees showed increased power, as well as a pronounced decrease in alpha frequencies indicating an increased cognitive load. This exploratory study stimulates further hypotheses on how coordination of brain and muscle activity is modulated after a lower limb amputation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.677
Threshold uncertainty score0.451

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.251
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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