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Record W4411407763 · doi:10.1056/nejmc2503347

Three Cases of Vertical Transmission of Clade Ib Mpox Virus

2025· letter· en· W4411407763 on OpenAlexafffundabout
Emmanuel Hasivirwe Vakaniaki, Nono-Raymond Kuispond Swar, Yuichiro Hirata, Eugene Bangwen, Isabel Brosius, Eddy Kinganda-Lusamaki, Seiya Ozono, Harutaka Katano, Laurent Gabanga Ndunge, Noëlla Mulopo-Mukanya, Jean-Claude Tshomba, Elise De Vos, Christophe Van Dijck, Papy Munganga, Guy Mukari, Yves Mujula, Divin Mazambi Mambo, Steeven Bilembo Kitwanda, Nadine Maliyamungu-Bubala, Léandre Mutimbwa-Mambo, Ian Crozier, Lori E. Dodd, Olivier Tshiani-Mbaya, Bienvenu Massamba Lebwaze, Espoir Bwenge Malembaka, Isaac Barhishindi, Susanne Krasemann, Robert Colebunders, Patrick DMC Katoto, Sheila Makiala‐Mandanda, Jason Kindrachuk, Anne W. Rimoin, Jean‐Jacques Muyembé‐Tamfum, Daniel Mukadi‐Bamuleka, Tony Wawina-Bokalanga, Sabin S. Nundu, Tadaki Suzuki, Raphaël Bulakali Chirimwami, Laurens Liesenborghs, Placide Mbala‐Kingebeni

Bibliographic record

VenueNew England Journal of Medicine · 2025
Typeletter
Languageen
FieldImmunology and Microbiology
TopicPoxvirus research and outbreaks
Canadian institutionsUniversity of Manitoba
FundersNational Cancer InstituteEuropean and Developing Countries Clinical Trials PartnershipCanadian Institutes of Health ResearchFonds Wetenschappelijk OnderzoekJapan Agency for Medical Research and Development
KeywordsCladeTransmission (telecommunications)VirologyVirusBiologyGeneticsComputer scienceTelecommunicationsPhylogeneticsGene

Abstract

fetched live from OpenAlex

sponsorship: Supported by the Belgian Directorate-General for Development Cooperation and Humanitarian Aid (grant number, 914010), the European and Developing Countries Clinical Trials Partnership EDCTP3 (grant numbers, 101195465 and 101195146), the Research Foundation-Flanders (grant numbers, G096222N, to Drs. Liesenborghs and Muyembe-Tamfum, and 12B1M24N, to Dr. Van Dijck), the African Coalition for Epidemic Research, Response, and Training network (which is part of the EDCTP2 Program, supported by the European Union under grant agreement RIA2016E-1612), and the Japan Agency for Medical Research and Development (grant numbers, JP24fk0108637 and JP24fk0108660) and in part by the National Cancer Institute, National Institutes of Health (contract number, 75N91019D00024), and the Canadian Institutes of Health Research and International Development Research Centre (grant number, MRR-184813). (Belgian Directorate-General for Development Cooperation and Humanitarian Aid|914010, European and Developing Countries Clinical Trials Partnership EDCTP3|101195465, European and Developing Countries Clinical Trials Partnership EDCTP3|101195146, Research Foundation-Flanders|G096222N, Research Foundation-Flanders|12B1M24N, African Coalition for Epidemic Research, Response, and Training network (EDCTP2 Program - European Union)|RIA2016E-1612, Japan Agency for Medical Research and Development|JP24fk0108637, Japan Agency for Medical Research and Development|JP24fk0108660, National Cancer Institute, National Institutes of Health|75N91019D00024, Canadian Institutes of Health Research and International Development Research Centre|MRR-184813)

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesResearch integrity, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.543
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.295
Teacher spread0.268 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2025
Admission routes3
Has abstractyes

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