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UNCONTROLLED DIABETES AS FACTOR AFFECTING COGNITIVE FUNCTION IN TYPE 2 DIABETES MELLITUS

2025· article· en· W4411464911 on OpenAlexaboutno aff
Astra Dea, Vivien Puspitasari, Tracy Solansa

Bibliographic record

VenueMNJ (Malang Neurology Journal) · 2025
Typearticle
Languageen
FieldHealth Professions
TopicArtificial Intelligence in Healthcare
Canadian institutionsnot available
Fundersnot available
KeywordsGlycated hemoglobinLogistic regressionMedicineCognitionDiabetes mellitusMontreal Cognitive AssessmentType 2 Diabetes MellitusType 2 diabetesBivariate analysisRisk factorInternal medicineStatisticsCognitive impairmentEndocrinologyMathematicsPsychiatry

Abstract

fetched live from OpenAlex

Background: Impairment or decline in cognitive function can be caused by various things, one of which is uncontrolled diabetes. In Indonesia, the research on the effect of blood sugar levels on cognitive function has been done, but still limited and less were using HbA1c. Objective: This research aims to find correlation between HbA1C level and cognitive function based on MoCA-Ina. Methods: This is a cross sectional study with a sample of 130 type 2 diabetes mellitus patients at Siloam Hospital Karawaci through a non-randomized purposive sampling method. Data collection was taken on January to May 2020 using medical record data for glycated hemoglobin (HbA1c) levels (cut off score 7%) and Montreal Cognitive Assessment ver. Indonesia (MoCA-Ina) score (cut off score 26) to evaluate the cognitive function. Statistical bivariate analysis performed using chi-square and multivariate analysis covariate variables using logistic regression. Results: Uncontrolled diabetes mellitus as shown by a high HbA1c level were significantly increase the risk of cognitive decline. The study showed a significant relationship between HbA1c levels with cognitive function (OR=5,98; CI 95% 2,25-15,58; p=0,000). A logistic regression analysis of various cognitive functions showed that memory was the most affected domain in patient with uncontrolled type 2 diabetes. Conclusion: Uncontrolled diabetes mellitus as shown by a high HbA1c level were significantly increase the risk of cognitive decline and the most affected domain was memory.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesResearch integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.036
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.053
GPT teacher head0.406
Teacher spread0.353 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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