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Record W4411500947 · doi:10.3389/fnagi.2025.1574275

The correlation between muscle strength, inhibitory function, and cognitive function in older adults with cognitive impairment: evidence from resting-state electroencephalography

2025· article· en· W4411500947 on OpenAlexaboutno aff
Mi Hu, Xing Wang

Bibliographic record

VenueFrontiers in Aging Neuroscience · 2025
Typearticle
Languageen
FieldNeuroscience
TopicEEG and Brain-Computer Interfaces
Canadian institutionsnot available
FundersNational Social Science Fund of China
KeywordsElectroencephalographyCognitionCognitive impairmentInhibitory postsynaptic potentialNeuroscienceCorrelationResting state fMRIPsychologyBrain functionMedicinePhysical medicine and rehabilitationAudiologyMathematics

Abstract

fetched live from OpenAlex

Objective This study explored the associations among muscle strength, inhibitory control, and cognitive function in older adults with cognitive impairment, focusing on related EEG changes. Methods Among 247 adults aged 70 and above, 120 with cognitive impairment were included. Assessments included the Montreal Cognitive Assessment (MoCA), Stroop task, grip strength, and resting-state EEG. Results Inhibitory control was significantly related to cognitive function: accuracy in congruent (r = 0.599, p < 0.001) and incongruent (r = 0.474, p < 0.001) conditions correlated positively with MoCA scores, while response times in both conditions showed negative correlations (r = –0.475 and –0.354, respectively, p < 0.001). EEG alpha1 (C3, P3, F7), alpha2 (P3, F8), and beta1 (P3, F7) power were significantly associated with both cognitive and inhibitory performance. Muscle strength was significantly positively correlated with specific EEG indicators, particularly alpha1 power at C4 (r = 0.212, p < 0.05), O2 (r = 0.204, p < 0.05), F8 (r = 0.225, p < 0.05), and T6 (r = 0.206, p < 0.05), as well as alpha2 power at C3 (r = 0.216, p < 0.05), P3 (r = 0.222, p < 0.05), P4 (r = 0.268, p < 0.001), F8 (r = 0.284, p < 0.001), and T5 (r = 0.218, p < 0.05). Conclusion Muscle strength may support cognitive and inhibitory function by influencing specific EEG activities. These findings highlight the neurophysiological links among muscle strength, cognition, and brain activity, offering potential biomarkers for early detection and intervention in cognitive decline.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.236
Teacher spread0.226 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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