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ENHANCED RECOVERY AFTER SURGERY GUIDELINES’ IMPACT ON VULVAR SURGICAL OUTCOMES: A retrospective cohort study

2025· preprint· en· W4411615404 on OpenAlexaffabout
Audrey Feng-Émond, Elise de Castro Hillmann, Vanessa Samouëlian

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldMedicine
TopicCardiac, Anesthesia and Surgical Outcomes
Canadian institutionsCentre Hospitalier de l’Université de MontréalUniversité de Montréal
Fundersnot available
KeywordsRetrospective cohort studyMedicineCohortGeneral surgeryCohort studySurgeryInternal medicine

Abstract

fetched live from OpenAlex

Objective The main objective is to analyze ERAS’s impact on vulvar oncology surgery. Design Retrospective observational cohort study Setting A single center, an academic reference center, and main referral for gynecology oncological patients in Quebec province, Canada. Population or Sample All patients who underwent surgery for vulvar cancer (or suspicious lesions) from the pre-ERAS (2015) and ERAS (2019-2021) periods were included. Methods The length of stay, postoperative complications, readmissions, reoperation and mortality rate were compared between pre-ERAS and ERAS cohorts. CHUM’s practices were compared to ERAS guidelines recommendations and ERAS Interactive Audit System (EIAS®). Proportions were used to analyze compliance with available guidelines. Main Outcome Measures The primary outcome of this study is ERAS’ impact on vulvar oncology surgery outcomes. Other outcomes include the analysis of CHUM’s compliance to ERAS guidelines and EIAS® ability to evaluate compliance for vulvar surgeries. Results 154 patients were included. Compliance increased from 28.5% % to 85.7%. We observed a reduction in length of stay (p=0.002), hospitalization complications(p=0.033) [respiratory (p=0.009), psychiatric (p=0.012) and pain (0.047)], hospitalization serious complications (p=0.011), postdischarge wound infections (p<0.001) with similar postdischarge complication rates (p=0.598). EIAS compliance algorithm only correctly interpreted 21.4% of recommendations. Conclusions ERAS implementation is beneficial regarding vulvar cancer surgery outcomes. All applicable guidelines should be grouped into a single checklist. EIAS compliance algorithm should be adapted to vulvar surgery. Funding This study received one scholarship grant from the PRogramme d’Excellence en Médecine pour l’Initiation En Recherche . Keywords ERAS, guideline, vulvar cancer, surgery, EIAS

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.139
Threshold uncertainty score0.276

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.002
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.358
Teacher spread0.331 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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