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Record W4411632148 · doi:10.1016/j.bas.2025.104307

Emerging advances in spinal cord injury: An introductory overview

2025· editorial· en· W4411632148 on OpenAlexaff
Michael G. Fehlings, Shintaro Honda, Peter Vajkoczy, Narihito Nagoshi

Bibliographic record

VenueBrain and Spine · 2025
Typeeditorial
Languageen
FieldMedicine
TopicSpinal Cord Injury Research
Canadian institutionsUniversity of TorontoUniversity Health Network
Fundersnot available
KeywordsMultidisciplinary approachMedicineSpinal cord injuryIntensive care medicineContext (archaeology)Clinical PracticeHealth careNeuroscienceSpinal cordPhysical therapyPsychology

Abstract

fetched live from OpenAlex

Spinal cord injury (SCI) remains a devastating condition with limited treatment options. This Focus Issue highlights recent clinical and translational advances across the continuum of SCI care from prehospital coordination to novel therapeutics. The articles cover multidisciplinary strategies during the early post-injury phase, including acute pre-hospital care and pragmatic alternatives for settings with limited medical resources. A historical perspective on the evolution of surgical timing and a comprehensive reappraisal of the pathophysiology of central cord syndrome provide valuable clinical context. Emerging diagnostic innovations are prominently featured, including novel biomarkers such as cerebrospinal fluid pressure dynamics, quantitative MRI, and navigated transcranial magnetic stimulation, which offer the potential to refine diagnosis and personalize prognostication. In parallel, emerging therapeutic technologies such as 3D-printed surgical guides and clinical applications of stem cell therapies represent significant advances in addressing long-standing challenges. The issue also includes comprehensive reviews of current classification systems and diagnostic criteria for both spine fractures and degenerative cervical myelopathy. Together, these contributions provide a multidisciplinary overview of the evolving landscape in SCI research and care, bridging basic science with clinical practice across diverse healthcare settings.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.013
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: Editorial
Teacher disagreement score0.007
Threshold uncertainty score0.025

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.013
Meta-epidemiology (narrow)0.0030.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0040.002
Science and technology studies0.0020.002
Scholarly communication0.0050.005
Open science0.0020.002
Research integrity0.0060.011
Insufficient payload (model declined to judge)0.0070.006

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.432
Teacher spread0.405 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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