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Record W4411641166 · doi:10.1371/journal.pone.0325930

Effects of age on the neural correlates of auditory working memory in cochlear implant users

2025· article· en· W4411641166 on OpenAlexafffund
Priyanka Prince, Claude Alain, Joseph Chen, Trung Le, Vincent Lin, Andrew Dimitrijevic

Bibliographic record

VenuePLoS ONE · 2025
Typearticle
Languageen
FieldNeuroscience
TopicHearing Loss and Rehabilitation
Canadian institutionsHealth Sciences CentreBaycrest HospitalPublic Health OntarioUniversity of TorontoSunnybrook Health Science Centre
FundersCanadian Institutes of Health Research
KeywordsWorking memoryAudiologyCochlear implantCognitionPsychologyNeural correlates of consciousnessYoung adultActive listeningMedicineDevelopmental psychologyNeuroscience

Abstract

fetched live from OpenAlex

Following a conversation in a noisy environment is challenging, especially for individuals who received cochlear implants (CIs) to remediate severe-to-profound hearing loss. CI users likely work harder than their normal-hearing counterparts to understand speech in adverse listening conditions. Recruiting cognitive resources can be taxing and may interfere with attentional regulation and working memory processes. Few studies have, however, examined the impact of CIs on the neural correlates of attention and working memory. We used a high-density electroencephalogram to investigate behavioural and neural correlates of auditory attention and working memory in 14 CI users and age-matched normal hearing (NH) controls (age ranges: 21-75). All participants completed an auditory n-back task with zero- and two-back memory load conditions. Behaviourally, CI users were slower in identifying targets during the two-back condition, especially older adults. The sensory-evoked responses were reduced in CI users compared to NH. With increasing memory load, younger CI users and NH controls displayed decreased amplitudes, while older CI users showed no change in amplitude. We also observed reduced frontal theta synchrony and greater alpha/beta desynchrony in CI users where alpha/beta in the left inferior frontal gyrus was related to slower response times in CI users. Attenuated frontotemporal connectivity was also evident compared to NH. These findings suggest that CI users adapt to higher task demands by allocating more attentional resources while encoding and maintaining stimuli in working memory. This pattern of activity potentially indexes a delay in identification and possible neural correlates of cognitive deficits while aging with a CI.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.246
Teacher spread0.209 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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