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Record W4411641220 · doi:10.1371/journal.pone.0324684

Prevalence of symptom exaggeration among North American independent medical evaluation examinees: A systematic review of observational studies

2025· review· en· W4411641220 on OpenAlexaff
Andrea Darzi, Li Wang, John J. Riva, Rami Z. Morsi, Rana Charide, Rachel Couban, Samer G. Karam, Kian Torabiardakani, Annie Lok, Shanil Ebrahim, Sheena Bance, Regina Kunz, Gordon H. Guyatt, Jason W. Busse

Bibliographic record

VenuePLoS ONE · 2025
Typereview
Languageen
FieldMedicine
TopicTraumatic Brain Injury Research
Canadian institutionsCentre for Addiction and Mental HealthMcMaster UniversityImpact
Fundersnot available
KeywordsMedicineObservational studyExaggerationConfidence intervalMEDLINEInterquartile rangeMeta-analysisCINAHLClinical psychologyDemographyInternal medicinePsychiatryPsychological intervention

Abstract

fetched live from OpenAlex

BACKGROUND: Independent medical evaluations (IMEs) are commonly acquired to provide an assessment of impairment; however, these assessments show poor inter-rater reliability. One potential contributor is symptom exaggeration by patients, who may feel pressure to emphasize their level of impairment to qualify for incentives. This study explored the prevalence of symptom exaggeration among IME examinees in North America, which if common may represent an important consideration for improving the reliability of IMEs. METHODS: We searched CINAHL, EMBASE, MEDLINE and PsycINFO from inception to July 08, 2024. We included observational studies that used a known-group design or multi-modal determination method. Paired reviewers independently assessed risk of bias and extracted data. We performed a random-effects model meta-analysis to estimate the overall prevalence of symptom exaggeration and explored potential subgroup effects for sex, age, education, clinical condition, and confidence in the reference standard. We used the GRADE approach to assess the certainty of evidence. RESULTS: We included 44 studies with 46 cohorts and 9,794 patients. The median of the mean age was 40 (interquartile range [IQR] 38-42). Most cohorts included patients with traumatic brain injuries (n = 31, 67%) or chronic pain (n = 11, 24%). Prevalence of symptom exaggeration across studies ranged from 17% to 67%. We found low certainty evidence suggesting that studies with a greater proportion of women (≥40%) may be associated with higher rates of exaggeration (47%, 95%CI 36-58) vs. studies with a lower proportion of women (<40%) (31%, 95%CI 28-35; test of interaction p = 0.02). Possible explanations include biological differences, greater bodily awareness, or higher rates of negative affectivity. We found no significant subgroup effects for type of clinical condition, confidence in the reference standard, age, or education. CONCLUSION: Symptom exaggeration may occur in almost 50% of women and in approximately a third of men undergoing IMEs. The high prevalence of symptom exaggeration among IME attendees provides a compelling rationale for clinical evaluators to formally explore this issue. Future research should establish the reliability and validity of evaluation criteria for symptom exaggeration and develop a structured IME assessment approach.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.032
metaresearch head score (Gemma)0.125
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.032
Threshold uncertainty score0.168

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0320.125
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0090.011
Bibliometrics0.0110.013
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0020.002
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.424
GPT teacher head0.460
Teacher spread0.037 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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