MétaCan
Menu
Back to cohort
Record W4411642054 · doi:10.14814/phy2.70437

The physiological effects of breath‐holding during high‐intensity exercise

2025· article· en· W4411642054 on OpenAlexafffund
Jeremy Walsh, James M. Ramsey, Nasimi A. Guluzade, Robin Faricier, Daniel A. Keir, Glen R. Belfry

Bibliographic record

VenuePhysiological Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiovascular and exercise physiology
Canadian institutionsToronto General HospitalLawson Health Research InstituteWestern University
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsBradycardiaHeart rateMedicineCardiologyInternal medicineBlood pressureVO2 maxTachycardiaApneaAnesthesia

Abstract

fetched live from OpenAlex

Abstract The purpose of this study was to determine the physiological effects of breath‐holding during high‐intensity exercise. Twenty participants (age: 23 ± 4 years, 10 females) performed 20 s sprints of simultaneous arm and leg ergometry exercise, under free‐breathing (FB) and breath‐holding (BH) conditions. Identical power outputs were sustained for both breathing conditions. Heart rate was significantly higher under the breath‐holding condition during exercise (FB = 118 ± 12 bpm versus BH = 131 ± 14 bpm; p < 0.001) but lower for 5 min post‐exercise (FB = 110 ± 16 bpm, BH = 102 ± 15 bpm, p = 0.003). Systolic blood pressure was higher under the breath‐holding condition post‐exercise (FB = 142 ± 18 mmHg, BH = 151 ± 15 mmHg, p = 0.03). Muscle deoxygenated hemoglobin was unchanged between conditions during exercise (FB = 2.7 ± 1.7 μM, BH = 2.6 ± 1.7 μM, p = 0.37) and no difference in post‐exercise blood lactate concentration was observed between conditions (FB = 9.3 ± 3.5 mmol.L −1 , BH = 8.2 ± 2.5 mmol.L −1 , p = 0.15). End‐tidal partial pressure of oxygen was reduced (FB = 111 ± 11 mmHg, BH = 76 ± 14 mmHg, p < 0.001) and oxygen uptake was increased (FB = 2.36 ± 0.63 L.min −1 , BH = 4.52 ± 0.73 L.min −1 , p < 0.001) under the breath‐holding condition immediately post‐exercise. Exercise‐induced tachycardia prevailed over apnea‐induced bradycardia during exercise, but residual effects of breath‐holding were evidenced by the observed bradycardia during recovery. These data suggest that intrinsic oxygen stores were sufficient to sustain the aerobic energy contribution during 20 s high‐intensity exercise while breath‐holding.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.755
Threshold uncertainty score0.624

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.255
Teacher spread0.246 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

Explore more

Same venuePhysiological ReportsSame topicCardiovascular and exercise physiologyFrench-language works237,207