Bibliographic record
Abstract
This study was undertaken to evaluate the antiurolithiac effect of ethanolic extract of RHUS MYSORENSIS (ERM) against calcium oxalate urolithiasis using male wistar rats.Urolithasis was induced by administration of 0.75% V/V ethylene glycol with 1%w/V ammonium chloride in drinking water for 3 days followed by only 0.75% v/v ethylene glycol for next 25 days.Antiurolithiatic activity was evaluated at four doses of ERM (viz.,250,350,450,550mg/kg) in curative and preventive regimen by estimating histological changes in kidney tissue and biochemical changes in urine, serum, and kidney tissue homogenate.Ethylene glycol-ammonium chloride feeding caused alteration in volume and levels of calcium, oxalate, phosphate, uric acid in the urine.The ERM treatment also increased urine volume but less than calculi induced animals.The ERM supplementation significantly prevented biochemical changes in the urine dose dependently.Supplementation with ERM prevented the elevation serum creatinine, uric acid and calcium, phosphate levels.The increased calcium, oxalate and phosphate levels in the kidney tissue of lithiatic rats were significantly reduced by the ERM treatment.The ERM supplementation also caused significant decrease in accumulation of calcium oxalate deposits, histological changes in the kidney tissue.These results indicate that administration RHUS MYSORENSIS extract reduced and prevented the growth of urinary stones.The possible mechanism underlined this effect is mediated collectively through diuretic properties and lowering the concentration of urinary stone forming constituents.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.994 | 0.983 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".