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Record W4411702401 · doi:10.1111/apt.70250

Expert Position Statement: Defining the Role of Intestinal Ultrasound in Assessing Constipation and Faecal Loading

2025· article· en· W4411702401 on OpenAlexaff
Ryan Mathias, Thomas M Goodsall, Claire E. Parker, Alice S. Day, Yoon‐Kyo An, Brandon Baraty, Chamara Basnayake, Jakob Begun, Ray Boyapati, Rebecca Burgell, Michael T. Dolinger, Giovanni Maconi, Kerri L. Novak, Shintaro Sagami, Rebecca L. Smith, Ashish Srinivasan, Stuart A. Taylor, Vipul Jairath, Christopher Ma, Robert V. Bryant

Bibliographic record

VenueAlimentary Pharmacology & Therapeutics · 2025
Typearticle
Languageen
FieldMedicine
TopicGastrointestinal motility and disorders
Canadian institutionsWestern UniversitySouth Health CampusUniversity of CalgaryLondon Health Sciences Centre
FundersNational Health and Medical Research CouncilUniversity of QueenslandSamsungUniversity of AdelaideGastroenterological Society of AustraliaCelltrionMater FoundationGilead SciencesSanofiMylanGlaxoSmithKlineHospital Research FoundationTillotts PharmaAmgenDr. Falk PharmaPfizerAstraZenecaEli Lilly and CompanyBristol-Myers Squibb
KeywordsMedicineConstipationUltrasoundEchogenicityInternal medicineRadiology

Abstract

fetched live from OpenAlex

BACKGROUND: Intestinal ultrasound has been proposed as a tool to assess non-inflammatory functional gastrointestinal disorders, including constipation and faecal loading. However, well-defined sonographic criteria for these conditions are currently lacking. AIM: To identify and establish specific sonographic parameters that could be used to assess constipation and faecal loading with intestinal ultrasound. METHODS: We conducted a Research and Development/University of California Los Angeles appropriateness method exercise. A multidisciplinary, international panel comprising 14 experts in adult and paediatric gastroenterology and one radiologist experienced in gastrointestinal imaging rated the appropriateness of 57 statements using a 9-point Likert scale over two rounds of voting. Based on the median panel rating and level of disagreement, statements were categorised as appropriate, inappropriate or uncertain. RESULTS: 43 statements were deemed appropriate after two rounds of voting, while three were rated as inappropriate and five as uncertain. Intestinal ultrasound was determined to be an appropriate modality for the assessment of faecal loading. Posterior acoustic shadowing and echogenic reflections were considered important sonographic parameters for the assessment of faecal loading. A rectal diameter of 30 mm was considered appropriate to define faecal loading in paediatric patients, although no recommendation was made for adult patients due to a paucity of data. CONCLUSION: The expert panel considered intestinal ultrasound an appropriate modality for evaluating constipation and faecal loading. Further prospective research is required, especially in adult patients, to define sonographic metrics of luminal contents to broaden its application in the assessment of functional gastrointestinal disorders.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.038
metaresearch head score (Gemma)0.102
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: none
Teacher disagreement score0.038
Threshold uncertainty score0.201

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0380.102
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0020.002
Scholarly communication0.0030.002
Open science0.0030.003
Research integrity0.0150.009
Insufficient payload (model declined to judge)0.0060.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.347
Teacher spread0.328 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2025
Admission routes1
Has abstractyes

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