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Record W4411716514 · doi:10.1002/imhj.70029

Effects of integrated programs for substance‐involved mothers on infant and child development outcomes: A systematic review and meta‐analysis

2025· review· en· W4411716514 on OpenAlexaff
Sophie Barriault, Mary Motz, Lamia Firasta, Hannah McDowell, Patrick Labelle, Nancy Poole, Nicole Racine

Bibliographic record

VenueInfant Mental Health Journal · 2025
Typereview
Languageen
FieldMedicine
TopicPrenatal Substance Exposure Effects
Canadian institutionsBritish Columbia Centre of Excellence for Women's HealthChildren's Hospital of Eastern OntarioLibrary and Archives CanadaUniversity of Ottawa
Fundersnot available
KeywordsPsycINFOCINAHLModerationPsychological interventionMeta-analysisMEDLINEMedicineChild developmentIntervention (counseling)PsychologyPsychiatry

Abstract

fetched live from OpenAlex

Maternal substance use is a pressing public health issue that confers risk for maternal health, the parent-infant relationship, and child development. Integrated interventions that jointly address maternal substance use and child development have shown promise for enhancing child outcomes. No research to date has focused exclusively on the outcomes of young children or examined potential moderators of the effect sizes of integrated programs. This review evaluates the pooled effect of integrated interventions for substance-involved mothers on the developmental outcomes of their children. A comprehensive search strategy was conducted in seven databases (APA PsycINFO, CINAHL, Cochrane CENTRAL, Embase, MEDLINE, Sociological Abstracts, Web of Science) from January 2011 and May 2023. Studies were included if they reported on an intervention with at least one substance use treatment and one parenting or child treatment service for substance-involved mothers of children under 6 years of age. A total of 21 studies met inclusion criteria, and 14 nonoverlapping studies reported on effect sizes with a pooled effect size of SMD = .470 (95% CI = .35, .59). There was a trend toward treatment duration being a significant moderator (p = .08). Additional high-quality studies are needed to demonstrate the long-term impact of these interventions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.009
metaresearch head score (Gemma)0.025
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.018
Threshold uncertainty score0.048

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0090.025
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0180.023
Bibliometrics0.0060.007
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0020.002
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.355
Teacher spread0.321 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueInfant Mental Health JournalSame topicPrenatal Substance Exposure EffectsFrench-language works237,207