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Record W4411718880 · doi:10.1021/acsnano.5c03911

Technology Roadmap of Micro/Nanorobots

2025· review· en· W4411718880 on OpenAlexafffund
Xiaohui Ju, Chuanrui Chen, Çağatay M. Oral, Semih Sevim, Ramin Golestanian, Mengmeng Sun, Negin Bouzari, Xiankun Lin, Mario Urso, Jong Seok Nam, Yujang Cho, Peng Xia, Fabian C. Landers, Shihao Yang, Azin Adibi, Nahid Taz, Raphael Wittkowski, Daniel Ahmed, Wei Wang, Veronika Magdanz, Mariana Medina‐Sánchez, Maria Guix, Naimat K. Bari, Bahareh Behkam, Raymond Kapral, Yaxin Huang, Jinyao Tang, Ben Wang, Konstantin I. Morozov, Alexander M. Leshansky, Sarmad Ahmad Abbasi, Hongsoo Choi, Subhadip Ghosh, Bárbara Borges-Fernandes, Giuseppe Battaglia, Peer Fischer, Ambarish Ghosh, Beatriz Jurado‐Sánchez, Alberto Escarpa, Quentin Martinet, Jérémie Palacci, Eric Lauga, Jeffrey L. Moran, Miguel A. Ramos‐Docampo, Brigitte Städler, Ramón Santiago Herrera Restrepo, Gilad Yossifon, James D. Nicholas, Jordi Ignés‐Mullol, Josep Puigmartí-Luis, Yutong Liu, Lauren D. Zarzar, C. Wyatt Shields, Longqiu Li, Shanshan Li, Xing Ma, David H. Gracias, Orlin D. Velev, Samuel Sánchez, M.J. Esplandiu, Juliane Simmchen, Antônio Lobosco, Sarthak Misra, Zhiguang Wu, Jinxing Li, Alexander Kuhn, Amir Nourhani, Tijana Marić, Ze Xiong, Amirreza Aghakhani, Yongfeng Mei, Yingfeng Tu, Fei Peng, Eric Diller, Mahmut Selman Sakar, Ayusman Sen, Junhui Law, Yu Sun, Abdon Pena‐Francesch, Katherine Villa, Huaizhi Li, Donglei Fan, Kang Liang, Tony Jun Huang, Xiangzhong Chen, Songsong Tang, Xueji Zhang, Jizhai Cui, Hong Wang, Wei Gao, Vineeth Kumar Bandari, Oliver G. Schmidt, Xianghua Wu, Jianguo Guan, Metin Sitti, Bradley J. Nelson, Salvador Pané, Li Zhang, Hamed Shahsavan, Qiang He, Il‐Doo Kim, Joseph Wang, Martin Pumera

Bibliographic record

VenueACS Nano · 2025
Typereview
Languageen
FieldPhysics and Astronomy
TopicMicro and Nano Robotics
Canadian institutionsUniversity of TorontoUniversity of Waterloo
FundersH2020 Future and Emerging TechnologiesDivision of Electrical, Communications and Cyber SystemsDivision of Civil, Mechanical and Manufacturing InnovationAir Force Office of Scientific ResearchNational Key Research and Development Program of ChinaEuropean Regional Development FundHORIZON EUROPE European Innovation CouncilH2020 European Research CouncilShanghai Rising-Star ProgramH2020 Marie Skłodowska-Curie ActionsSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungJunta de Comunidades de Castilla-La ManchaMinisterio de Ciencia, Innovación y UniversidadesScience, Technology and Innovation Commission of Shenzhen MunicipalityNextGenerationEUIsrael Science FoundationShanghaiTech UniversityNational Research Foundation of KoreaArmy Research OfficeNational Institute of Biomedical Imaging and BioengineeringGrantová Agentura České RepublikyGeneralitat de CatalunyaVirginia Polytechnic Institute and State UniversityNational Natural Science Foundation of ChinaScience and Technology Commission of Shanghai MunicipalityNatural Sciences and Engineering Research Council of CanadaAlfred P. Sloan FoundationDeutsche ForschungsgemeinschaftDivision of Chemical, Bioengineering, Environmental, and Transport SystemsResearch Grants Council, University Grants CommitteeKey Technologies Research and Development ProgramNational Science Foundation
KeywordsNanoroboticsCommercializationNanotechnologyComputer scienceSustainabilitySystems engineeringBiomedicineEngineering ethicsSoftware deploymentGrand ChallengesManagement scienceEngineering managementEngineeringBusinessArtificial intelligenceMaterials science

Abstract

fetched live from OpenAlex

, the field of micro/nanorobots has evolved from science fiction to reality, with significant advancements in biomedical and environmental applications. Despite the rapid progress, the deployment of functional micro/nanorobots remains limited. This review of the technology roadmap identifies key challenges hindering their widespread use, focusing on propulsion mechanisms, fundamental theoretical aspects, collective behavior, material design, and embodied intelligence. We explore the current state of micro/nanorobot technology, with an emphasis on applications in biomedicine, environmental remediation, analytical sensing, and other industrial technological aspects. Additionally, we analyze issues related to scaling up production, commercialization, and regulatory frameworks that are crucial for transitioning from research to practical applications. We also emphasize the need for interdisciplinary collaboration to address both technical and nontechnical challenges, such as sustainability, ethics, and business considerations. Finally, we propose a roadmap for future research to accelerate the development of micro/nanorobots, positioning them as essential tools for addressing grand challenges and enhancing the quality of life.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.006
Threshold uncertainty score0.019

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.002
Science and technology studies0.0010.001
Scholarly communication0.0020.003
Open science0.0010.001
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0060.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.296
Teacher spread0.282 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations78
Published2025
Admission routes2
Has abstractyes

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