MétaCan
Menu
Back to cohort
Record W4411750811 · doi:10.1093/plphys/kiaf283

Gene expression landscape of the <i>Brassica napus</i> seed reveals subgenome bias in both space and time

2025· article· en· W4411750811 on OpenAlexafffund
Dylan J. Ziegler, Deirdre Khan, Jenna L. Kalichuk, Michael G. Becker, Asher Pasha, Nicholas J. Provart, Mark F. Belmonte

Bibliographic record

VenuePLANT PHYSIOLOGY · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicChromosomal and Genetic Variations
Canadian institutionsUniversity of TorontoUniversity of Manitoba
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsBrassicaGeneGene expressionBiologyGeneticsExpression (computer science)Space (punctuation)Computational biologyBotanyComputer science

Abstract

fetched live from OpenAlex

Brassica napus (canola; AnAnCnCn) contains both complete diploid genomes from its progenitors Brassica rapa (An) and Brassica oleracea (Cn). Despite growing knowledge of the gene expression landscape of the B. napus seed, little is known about subgenome bias underpinning the development of specific cells and tissues across the seed lifecycle. Here, we present a large-scale transcriptome atlas of the B. napus seed, including both the maternal seed coat and filial embryo and endosperm subregions. We report on extensive, global Cn subgenome bias throughout development and use homoeologous gene pairs to describe how subgenomic bias differs across subregions. We find that subgenome bias is most prominent during early development and that the maternal subregions experience far more asymmetric transcript accumulation in favor of the Cn subgenome. In particular, the unexpectedly distinct transcriptome profile of the chalazal pole indicates the unique developmental processes involved within the chalaza. Furthermore, we report that genes integral to seed storage comprise a large portion of the transcriptome of mature seeds, especially within the embryo, and that gene pairs previously documented to be instrumental in seed development exhibit low transcriptional bias. This work represents an important synthesis of polyploid transcriptomics in seed biology and provides a comprehensive overview of the B. napus gene expression landscape in both space and time.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.903
Threshold uncertainty score0.095

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.200
Teacher spread0.187 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2025
Admission routes2
Has abstractyes

Explore more

Same venuePLANT PHYSIOLOGYSame topicChromosomal and Genetic VariationsFrench-language works237,207