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Record W4411760614 · doi:10.18502/jabs.v15i2.18087

Enhancing Wound Healing in Aesthetic Surgery: The Role of Chitosan–Moringa oleifera Gel

2025· article· en· W4411760614 on OpenAlexaboutno aff
Shirin Hajimazdarani, Shahin Mohammad Sadeghi, Naser Mozafari, Keshvad Hedayatyanfard, Neda Baghban, Hassan Habibi

Bibliographic record

VenueJournal of Advanced Biomedical Sciences · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicMoringa oleifera research and applications
Canadian institutionsnot available
Fundersnot available
KeywordsMoringaChitosanWound healingTraditional medicineMedicineSurgeryChemistry

Abstract

fetched live from OpenAlex

Background & Objectives: This study aimed to evaluate the efficacy of chitosan gel infused with the hydroalcoholic extract of Moringa oleifera leaf powder in promoting wound healing and reducing scar formation following cosmetic breast surgery. Materials & Methods: A total of 42 patients undergoing cosmetic breast surgery were enrolled in this randomized controlled study. Each patient’s breast was divided into two lateral hemispheres: one side received Moringa oleifera gel, while the other served as a control with a placebo gel. The gels were applied for two weeks postoperatively. Scar appearance was assessed at two weeks and three months post-surgery using the Vancouver Scar Scale (VSS), which evaluates vascularity, pigmentation, elasticity, and height. Data were analyzed to compare outcomes between the treated and control sites. Results: Of the initial 42 patients, 36 completed the study. Twenty-five and thirty-one patients were evaluated at the two-week and three-month follow-ups, respectively. Wounds treated with the Moringa-infused gel demonstrated an 84% improvement in healing compared to those treated with the placebo. Statistically significant improvements were observed in all evaluated parameters—including vascularity, pigmentation, height, and elasticity—in favor of the Moringa oleifera gel. Conclusions: Chitosan gel infused with the hydroalcoholic extract of Moringa oleifera leaf powder significantly enhances wound healing and improves scar appearance following cosmetic breast surgery. These findings highlight its potential as a valuable adjunct in postoperative wound care for reducing scarring and promoting tissue regeneration.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.357
Threshold uncertainty score0.217

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.002
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.287
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

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