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Record W4411760672 · doi:10.1093/conphys/coaf042

Putative neural and endocrine control of thermal acclimation in fish

2025· article· en· W4411760672 on OpenAlexafffund
Robine H. J. Leeuwis, Rachael Morgan, Anna H. Andreassen, Lorena Silva‐Garay, Zara‐Louise Cowan, Eirik R. Åsheim, Jérémy De Bonville, Sandra A. Binning, Graham D. Raby, Fredrik Jutfelt

Bibliographic record

VenueConservation Physiology · 2025
Typearticle
Languageen
FieldEnvironmental Science
TopicPhysiological and biochemical adaptations
Canadian institutionsTrent UniversityUniversité de Montréal
FundersEuropean Research CouncilGroupe de recherche interuniversitaire en limnologieNorges ForskningsrådSociety for Experimental BiologyCompany of Biologists
KeywordsAcclimatizationBiologyGadusAtlantic codHormoneAnimal scienceEndocrine systemRespiratory compensationFish <Actinopterygii>EndocrinologyFisheryPhysiologyEcologyAnaerobic exercise

Abstract

fetched live from OpenAlex

Abstract Fishes can acclimate to a range of temperatures. However, the signalling factors controlling thermal acclimation are not well understood. Here, in two experiments, we examined the putative roles of plasma-borne factors (e.g. hormones) and skin thermoreception in the acclimation process. In experiment 1, 16°C-acclimated Atlantic cod (Gadus morhua) were subjected to a transfusion treatment by injecting plasma from 8°C (cold), 16°C (control) or 21°C (warm) acclimated cod, 10 times over four days. Plasma was collected from donor cod that were 24 h into their acclimation. In experiment 2, 16°C-acclimated goldsinny wrasse (Ctenolabrus rupestris) were exposed to an immersion treatment consisting of 10 s immersions in an 8°C (cold), 16°C (control) or 24°C (warm) water bath, repeated five times daily for five days. These brief immersions allowed for changes to skin temperature but not deeper tissues. Following these treatments, we measured the critical thermal maximum (CTmax) of all fish and the standard metabolic rate (SMR) in cod. Neither the immersions nor transfusions affected fish CTmax. However, the SMR was elevated in cod receiving plasma from cold-acclimated donors, suggesting that circulating molecules transferred from donors had initiated metabolic compensation in recipients. Thyroid hormone plasma levels were not different amongst acclimated donors and thus appear not to have been involved in the metabolic compensation. Our experiments found no evidence that brief, repeated cutaneous exposures to temperature changes can trigger acclimation, but do demonstrate a potential role of haematological endocrine control in metabolic acclimation, although further experiments will be required to investigate this process.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.948
Threshold uncertainty score0.162

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.242
Teacher spread0.229 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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