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Record W4411882235 · doi:10.1186/s12915-025-02284-x

Biomonitoring 2.0 Refined: observing local change through metaphylogeography using a community-based eDNA metabarcoding monitoring network

2025· article· en· W4411882235 on OpenAlexafffund
Andrew C. Riley, Michael Wright, Teresita M. Porter, Victoria Carley Maitland, Donald J. Baird, Mehrdad Hajibabaei

Bibliographic record

VenueBMC Biology · 2025
Typearticle
Languageen
FieldEnvironmental Science
TopicEnvironmental DNA in Biodiversity Studies
Canadian institutionsUniversity of New BrunswickUniversity of Guelph
FundersEnvironment and Climate Change CanadaGovernment of CanadaOntario GenomicsNature Conservancy of CanadaGenome Canada
KeywordsBiomonitoringIntraspecific competitionBiologyEcologyDNA barcodingBiological dispersalBiodiversityAmpliconEvolutionary biologyPolymerase chain reactionGenetics

Abstract

fetched live from OpenAlex

BACKGROUND: Biological data at different levels of organization is essential to support actions to mitigate the current biodiversity crisis. DNA metabarcoding is an established method to detect species/genus level taxa from bulk samples leading the way for a Biomonitoring 2.0 framework. Biomonitoring 2.0 Refined adds another dimension to Biomonitoring 2.0-high-throughput, scalable DNA metabarcoding with a higher resolution at the intraspecific level. Intraspecific diversity is key to understanding the distribution and movement of local populations for conservation efforts. Gaining reliable intraspecific information from metabarcoding data, however, is challenging due to qualitative/quantitative issues that can impact validity of the inference. RESULTS: Samples collected for the STREAM community-based monitoring project were used to perform an intraspecific genetic variation analysis on benthic arthropods. We targeted two non-overlapping cytochrome c oxidase subunit 1 mitochondrial DNA amplicons to assess the reproducibility of our results. Samples from the Rocky Mountains were grouped into four regions separated by mountain ranges. Significant separation (PERMANOVA, p value < 0.05) of Sørensen dissimilarity between regions was observed for community and intraspecific levels, fitting the expectation that mountains are barriers to dispersal. Two of the regions showed significant spatial structuring (Mantel test, p value < 0.05) at the intraspecific level, while all regions showed significant structuring at the community level. Results were consistent across both amplicons. CONCLUSIONS: We show that DNA metabarcoding is applicable to intraspecific diversity analysis and it is robust to different amplicons. This paves the way for Biomonitoring 2.0 Refined, which can provide much needed fine-scale biodiversity data for ecological assessments and conservation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.085
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0010.002
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.136
GPT teacher head0.318
Teacher spread0.182 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2025
Admission routes2
Has abstractyes

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