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Record W4411885694 · doi:10.3390/brainsci15070700

Are Changes in Corticomotor Excitability Associated with Improved Arm Functional Performance Following a Tailored Strength Training Intervention in Chronic Stroke Survivors?

2025· article· en· W4411885694 on OpenAlexafffund
Stephania Palimeris, Yekta Ansari, Anthony Remaud, François Tremblay, Hélène Corriveau, Marie‐Hélène Boudrias, Marie-Hélène Milot

Bibliographic record

VenueBrain Sciences · 2025
Typearticle
Languageen
FieldNeuroscience
TopicTranscranial Magnetic Stimulation Studies
Canadian institutionsCentre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-MontréalUniversité de SherbrookeUniversity of OttawaCentre Intégré de Santé et de Services Sociaux des LaurentidesBruyèreCentre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-JeanJewish Rehabilitation HospitalMcGill UniversityCentre for Interdisciplinary Research in Rehabilitation
FundersCanada First Research Excellence FundFondation Brain Canada
KeywordsTranscranial magnetic stimulationNeuroplasticityPhysical medicine and rehabilitationTranscranial direct-current stimulationMotor cortexStroke (engine)RehabilitationPsychologyBrain stimulationSilent periodMedicinePrimary motor cortexStimulationLateralization of brain functionPhysical therapyNeuroscience

Abstract

fetched live from OpenAlex

BACKGROUND/OBJECTIVES: We showed that a tailored strengthening intervention based on the size of motor evoked potentials (MEPs) elicited by transcranial magnetic stimulation (TMS) in the affected hemisphere resulted in an improved affected arm function, regardless of stroke severity. Also, adding anodal transcranial direct stimulation (atDCS) during training did not alter the results as participants receiving real or sham stimulation showed similar gains. The goal of this study was to report on the changes in basic measures of corticomotor excitability in response to the intervention and to determine whether these changes were influenced by tDCS and correlated with those measured in arm function. METHODS: The TMS measures consisted of the resting motor threshold (rMT), MEP amplitude at rest, and the silent period (SP) duration. Clinical outcomes included the Box and Block test (BBT) and grip strength (GS). RESULTS: > 0.06). CONCLUSIONS: As observed for clinical measures, atDCS did not influence corticomotor excitability. The absence of an increase in the excitability of the affected hemisphere and important associations between changes in corticomotor excitability and clinical gains suggest that factors other than brain plasticity could mediate gains in arm function. Further investigations are required regarding the role of tDCS in stroke rehabilitation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.064
GPT teacher head0.299
Teacher spread0.235 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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