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Record W4411917937 · doi:10.3389/fneur.2025.1587060

Repetitive transcranial magnetic stimulation for enhancing motor function after spinal cord injury: a narrative review

2025· review· en· W4411917937 on OpenAlexaff
Francisco Benavides, Mary Grace Shine, Filip Stefanovic, Robert Chen, Hang Jin Jo

Bibliographic record

VenueFrontiers in Neurology · 2025
Typereview
Languageen
FieldNeuroscience
TopicTranscranial Magnetic Stimulation Studies
Canadian institutionsKrembil Foundation
Fundersnot available
KeywordsTranscranial magnetic stimulationSpasticityPhysical medicine and rehabilitationSpinal cord injuryRehabilitationNarrative reviewMedicinePsychologyNeuroscienceBrain stimulationStimulationSpinal cordIntensive care medicine

Abstract

fetched live from OpenAlex

Spinal cord injury (SCI) often leads to disabilities that significantly impact quality of life, highlighting the need for effective rehabilitation strategies. Repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising neuromodulatory approach to enhance neuronal plasticity and promote motor recovery following SCI. This narrative review examines the current state of evidence regarding the therapeutic use of rTMS for motor function recovery after SCI and outlines key methodological considerations to guide future research. To address these aims, we summarize various rTMS techniques and evaluate their overall efficacy in improving motor function in individuals with SCI. Among the fourteen studies reviewed, early rTMS protocols primarily utilized low-frequency stimulation, whereas more recent approaches have adopted higher frequencies and more complex patterned protocols. Despite considerable heterogeneity in stimulation parameters, most studies reported beneficial effects of rTMS, including reduction in spasticity and improvements in voluntary motor function of both upper and lower limbs. These findings demonstrate that rTMS holds promise as an effective tool for SCI rehabilitation, with limited to moderate evidence supporting reductions in spasticity, increased muscle strength, and enhanced functional outcomes. However, many of these findings are derived from small sample sizes, varied protocols, and studies lacking rigorous control conditions. The review emphasizes the need for standardized functional and electrophysiological assessments to systematically evaluate motor outcomes following rTMS interventions. Additionally, larger, well-controlled clinical trials incorporating consistent physical therapy protocols are essential to confirm the efficacy of rTMS.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.004
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0040.004
Science and technology studies0.0000.000
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.344
Teacher spread0.313 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes1
Has abstractyes

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