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Record W4411985904 · doi:10.1016/j.arthro.2025.06.032

Patient‐Specific Cutting Guides Provide Consistent Planned Correction and Preserved Joint Line Obliquity for Double‐Level Knee Osteotomy

2025· article· en· W4411985904 on OpenAlexfundaboutno aff
Xinlong Ma, Zhihu Zhao, Haohao Bai, Songqing Ye, Bin Zhao, Wei Luo

Bibliographic record

VenueArthroscopy The Journal of Arthroscopic and Related Surgery · 2025
Typearticle
Languageen
FieldMedicine
TopicTotal Knee Arthroplasty Outcomes
Canadian institutionsnot available
FundersDigital Technology SuperclusterNational Key Clinical Specialty Discipline Construction Program of ChinaTianjin Municipal Science and Technology BureauNational Natural Science Foundation of China
KeywordsOsteotomyJoint (building)Knee JointLine (geometry)OrthodonticsComputer sciencePhysical medicine and rehabilitationMedicineSurgeryEngineeringMathematicsStructural engineeringGeometry

Abstract

fetched live from OpenAlex

PURPOSE: To evaluate clinical outcomes and accuracy of patient-specific cutting guides (PSCGs) in double-level knee osteotomy (DLO) patients over a minimum 24-month follow-up. METHODS: This single-center retrospective case series included consecutive patients who underwent DLO using PSCGs from December 2016 to May 2022. Inclusion criteria comprised symptomatic knee osteoarthritis with varus/valgus malalignment, planned double-level correction, and a minimum 24-month follow-up. Primary outcomes were functional improvement (Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC] scores) and complications; secondary outcomes included alignment accuracy (hip-knee-ankle, medial proximal tibial angle, lateral distal femoral angle, joint line obliquity, joint line convergence angle) and patient satisfaction. The WOMAC scores and achievements of minimal clinically important difference (MCID) and patient acceptable symptom state (PASS) were compared between patients with and without postoperative effusion-synovitis. Statistical analysis used the Mann-Whitney U test for alignment accuracy and paired t tests for functional outcomes. RESULTS: Among 31 patients (35 knees), there was a mean 36.2-month follow-up (range, 24-91 months). Patients' average age was 59.3 ± 5.14 years with a body mass index of 22.1 ± 1.8. Hip-knee-ankle improved from 163.9° to 181.1°, medial proximal tibial angle from 83.9° to 91.5°, lateral distal femoral angle from 94.7° to 85.7°, and joint line convergence angle from 5.6° to 2.4° (all preoperative to postoperative P < .05). Postoperative values showed no significant difference versus planned values (all P > .05). Preoperative joint line obliquity (4.71° ± 2.12°) significantly improved to 2.31° ± 2.02° postoperatively (P = .019), with no significant difference from the target (2.10° ± 1.53°, P = .526). WOMAC total scores decreased from 41.6 to 22.4 (P < .001), with 100% achieving the MCID. PASS rates varied: WOMAC pain (85.3%), stiffness (67.6%), physical function (94.1%), and total (79.4%). Complications included 2 femoral and 1 tibial hinge fractures, plus 6 venous thromboses (all resolved with rivaroxaban). Patient satisfaction was high (26/31 highly satisfied). CONCLUSIONS: DLO with PSCGs achieved consistent alignment with preoperative plans, preserved physiological joint line orientation, and sustained functional improvements over 36.2 months. All patients met the MCID for WOMAC total scores, with 94.1% attaining PASS in physical function and 85.3% in pain subdomains at a minimum 24-month follow-up. LEVEL OF EVIDENCE: Level IV, retrospective case series.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.281
Teacher spread0.244 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2025
Admission routes2
Has abstractyes

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