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The Prevalence and Incidence of Depression among Visually Impaired People: A Systematic Review and Meta-Analysis Protocol

2025· review· en· W4412032222 on OpenAlexaff
Pankaew Tantirattanakulchai, Nuchanad Hounnaklang, Nanda Win, Suchon Tepjan, Pear Pongsachareonnont

Bibliographic record

VenueF1000Research · 2025
Typereview
Languageen
FieldMedicine
TopicOphthalmology and Visual Impairment Studies
Canadian institutionsQueen's University
FundersChulalongkorn University
KeywordsFunnel plotMeta-analysisPublication biasSystematic reviewMedicineMEDLINEDepression (economics)Study heterogeneityProtocol (science)Incidence (geometry)PopulationPsychiatryGerontologyEnvironmental healthAlternative medicinePathology

Abstract

fetched live from OpenAlex

Background: Disability is widely acknowledged as a major contributor to depression, which is a prevalent mental health condition that profoundly affects individuals, especially those with visual impairments. Objectives: This develops a protocol for a systematic review and meta-analysis aim to examine the prevalence and incidence of depression among visually impaired people globally. Methods: This systematic review and meta-analysis will be conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA-P) guidelines. A thorough search will be conducted using the PubMed, MEDLINE, EMBASE, and ProQuest databases to identify relevant studies published between January 1, 2011, and August 31, 2024, without limitations on language. Two out of three independent reviewers will screen the abstracts and full-text articles, extract data, and assess the risk of bias. Heterogeneity among the included studies will be evaluated individually. Meta-analysis of the pooled prevalence and incidence estimates will be conducted using the metaprop function in StataBE 18.0. Publication bias will be assessed through funnel plot analysis and Egger's test. Conclusion: This protocol defines the planned scope and methodology for a forthcoming systematic review and meta-analysis, which aims to provide updated evidence on the prevalence and incidence of depression among individuals with visual impairment. Accordingly, it will facilitate a systematic review and meta-analysis to address the existing research gap by providing precise estimates of the pooled prevalence and incidence of depression in this population. The findings will offer valuable insights to inform public health policy, advocate for further research, and underscore the critical need to prioritize the mental health concerns of individuals with visual impairment. Systematic review registration: The protocol has been registered on the Open Science Framework (OSF) Registries with the Registration DOI: 10.17605/OSF.IO/6J4Y2.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmano category
Domain: not available · Genre: Protocol
About the Canadian research system: no · About a Canadian topic: no
Meta-analysishigh
gptno category
Domain: not available · Genre: Protocol
About the Canadian research system: no · About a Canadian topic: no
Systematic reviewhigh
models splitAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.719
Threshold uncertainty score0.811

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0070.001
Bibliometrics0.0000.002
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.127
GPT teacher head0.521
Teacher spread0.394 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

The models applied no category: nothing in the taxonomy fit this work.

The models disagree on parts of this classification; every voice is preserved in the section at the end of the page.

Study designMeta-analysis · Systematic review
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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