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Record W4412034995 · doi:10.1186/s12890-025-03778-8

Resilience and health-related quality of life in patients with pulmonary diseases receiving ambulatory oxygen therapy − 24-month follow-up results

2025· article· en· W4412034995 on OpenAlexaboutno aff
Siiri Isokääntä, Harri Sintonen, Merja Kokki

Bibliographic record

VenueBMC Pulmonary Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicChronic Obstructive Pulmonary Disease (COPD) Research
Canadian institutionsnot available
FundersHengityssairauksien Tutkimussäätiö
KeywordsMedicineAmbulatoryQuality of life (healthcare)Intensive care medicineResilience (materials science)Oxygen therapyInternal medicineNursing

Abstract

fetched live from OpenAlex

PURPOSE: There are scarce data on the development of health-related quality of life (HRQoL) over time and how psychological factors affect patients' adaptation to severe pulmonary diseases. This prospective 24-month follow-up study assessed HRQoL and its associations with anxiety, depression, resilience, and life satisfaction in pulmonary disease patients receiving ambulatory oxygen therapy. METHODS: We enrolled 47 patients who were prescribed ambulatory oxygen therapy for severe pulmonary diseases, and 3 months of data have been published previously. Patients completed five questionnaires at baseline and at 3, 6, 12 and 24 months: the 15D HRQoL instrument, the Hospital Anxiety and Depression Scale (HADS), the Life Satisfaction Scale-4, the Resilience Scale-25, and the Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST 2.0). The primary outcome was the HRQoL at 24 months. RESULTS: At 24 months, data were available for 19 patients (response rate 40%). Patients had very low HRQoL at baseline, which decreased substantially during the 24-month follow-up. There was a strong inverse correlation between HRQoL and anxiety, depression and life satisfaction and a strong positive correlation with resilience. However, half of the patients with severe pulmonary diseases receiving ambulatory oxygen therapy who had better psychological functioning were happy with life and did not feel lonely at all. Patient satisfaction with assistive technology and services was high. CONCLUSIONS: A low HRQoL in patients with severe pulmonary disease is strongly associated with poor psychological functioning. As anxiety, depression and resilience are modifiable factors, these factors should be evaluated in patients prescribed ambulatory oxygen therapy. TRIAL REGISTRATION: ClinicalTrials.gov Protocol Record 507A023. Registered 17 September 2020 - Registered, https://clinicaltrials.gov/ct2/results?cond=&term=NCT04554225&cntry=&state=&city=&dist= .

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.036
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0010.002
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.323
Teacher spread0.286 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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