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Record W4412073726 · doi:10.1249/mss.0000000000003812

Effect of 24-h Sleep Deprivation on Whole-Body Heat Loss in Older Males during Exercise in the Heat

2025· article· en· W4412073726 on OpenAlexaff
Nicholas J. Koetje, Nathalie V. Kirby, Fergus K. O’Connor, Brodie J. Richards, Kristina‐Marie T. Janetos, Leonidas G. Ioannou, Glen P. Kenny

Bibliographic record

VenueMedicine & Science in Sports & Exercise · 2025
Typearticle
Languageen
FieldMedicine
TopicThermoregulation and physiological responses
Canadian institutionsSocial Sciences and Humanities Research CouncilOttawa HospitalUniversity of Ottawa
Fundersnot available
KeywordsSleep deprivationMedicineThermoregulationSleep (system call)Internal medicineCircadian rhythm

Abstract

fetched live from OpenAlex

BACKGROUND: Older adults commonly experience sleep deprivation, which has been observed to alter thermoregulatory function in young adults. This may exacerbate risks of heat-related injury and illness during heat stress, due to age-related reductions in heat loss capacity. However, whether sleep deprivation modulates thermoregulatory function in older adults remains unclear. Thus, we aimed to assess the impact 24 h of total sleep deprivation has on whole-body heat loss during exercise-heat stress in older adults. METHODS: Following either a night of normal sleep or 24-h sleep deprivation, 10 older males (mean (SD); age 61 (4) yr) performed three 30-min exercise bouts at incrementally increasing rates of metabolic heat production (150, 200, 250 W·m -2 ), each separated by 15-min rest in hot, dry conditions (40°C, ~13% relative humidity). Whole-body total (dry + evaporative) heat loss and metabolic heat production were measured continuously using direct and indirect calorimetry, respectively, and used to calculate body heat storage. RESULTS: Peak whole-body total loss (mean difference (95% confidence interval), -12 (-20 to -3) W·m -2 ; P = 0.010) was reduced and body heat storage (0.60 (0.32 to 0.89) kJ·min -1 ; P = 0.002) increased during high-intensity exercise following sleep deprivation compared with normal sleep. However, evaporative heat loss (-10 (-20 to 1) W·m -2 ; P = 0.062) and dry heat gain (-2 (-9 to 5) W·m -2 ; P = 0.512) were not different between conditions. CONCLUSIONS: Sleep deprivation impaired whole-body total heat loss in older males, leading to greater heat storage during exercise-heat stress. Thus, sleep-deprived older adults performing prolonged high-intensity exercise in hot conditions may be at a heightened risk of heat-related illness or injury.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.305
Teacher spread0.293 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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