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Reliability and validity of the Pediatric PainSCAN: a screening tool for pediatric neuropathic pain and complex regional pain syndrome

2025· article· en· W4412080606 on OpenAlexaff
Giulia Mesaroli, Aileen M. Davis, Anthony V. Perruccio, Kristen M. Davidge, Fiona Campbell, Naiyi Sun, Suellen M. Walker, Courtney W. Hess, Laura E. Simons, Deirdre Logan, Jennifer Stinson

Bibliographic record

VenuePain · 2025
Typearticle
Languageen
FieldMedicine
TopicPain Management and Treatment
Canadian institutionsInstitute for Clinical Evaluative SciencesUniversity Health NetworkUniversity of TorontoSickKids FoundationHospital for Sick ChildrenPublic Health Ontario
FundersPlastic Surgery FoundationNational Institute of Arthritis and Musculoskeletal and Skin DiseasesMAYDAY Fund
KeywordsNeuropathic painIntraclass correlationConvergent validityComplex regional pain syndromeMedicinePhysical therapyReliability (semiconductor)Concurrent validityPain assessmentValidityPhysical medicine and rehabilitationPsychometricsAnesthesiaClinical psychologyPain management

Abstract

fetched live from OpenAlex

ABSTRACT: The Pediatric PainSCAN is the first screening tool for neuropathic pain (NP) and complex regional pain syndrome (CRPS) designed for pediatrics. Prior research developed the tool and established content validity. The tool has 3 parts, part A is a preface (pain location, severity, duration), part B discriminates NP or CRPS from other pain conditions, and part C discriminates CRPS from NP. This study aimed to evaluate the tool's reliability and validity. A multicentre cross-sectional survey was administered to participants with NP, CRPS, and other pain conditions in pediatric chronic pain clinics. Test-retest reliability was evaluated by readministering the tool after 7 days. Criterion validity (sensitivity [SE] and specificity [SP]) was evaluated by comparing participant scores to a clinician diagnosis. Convergent validity was evaluated by comparing participant scores on the tool to existing NP screening tools. Participants (N = 221; 56 with NP, 57 with CRPS, 108 with other pain) were aged 9 to 18 years and 81% female. Test-retest reliability (intraclass correlation coefficients part B = 0.76 and part C = 0.82) was sufficient (>0.70). Criterion validity (part B: SE 76%, SP 63%; part C: SE 83%, SP 77%) was sufficient (>70%) except for SP of part B. Convergent validity was sufficient (correlation coefficients aligned with hypotheses: painDETECT [0.73], self-report Leeds Assessment of Neuropathic Symptoms and Signs [0.73], and Patient-Reported Outcome Measurement Information System Neuropathic Pain Quality [0.59]). The Pediatric PainSCAN demonstrated sufficient reliability and validity to screen for NP and CRPS in pediatric chronic pain clinics. Future research is needed to evaluate the tool in other settings and determine the utility of implementing the tool in clinical practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.011
metaresearch head score (Gemma)0.025
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.011
Threshold uncertainty score0.060

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0110.025
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.270
Teacher spread0.228 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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