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Record W4412087326 · doi:10.1016/j.xgen.2025.100926

Landscape and m6A post-transcriptional regulation of soybean proteome

2025· article· en· W4412087326 on OpenAlexaff
Qing Yang, Zhiyang Hou, Linxia Li, Leili Wang, Shang‐Tong Li, Yaping Li, Xuemin Zhang, Huanwei Huang, Yunzhuo Ke, Xiaofei Ma, Zexuan Wu, Zhi Liu, Xiaolei Shi, Chaofan Liu, Chen Meng, Hai Du, Mingxun Chen, Xiaofeng Gu, Zhe Yan, Faming Wang, Xiaofang Luo, Long Yan, Zhe Liang

Bibliographic record

VenueCell Genomics · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicRNA modifications and cancer
Canadian institutionsBiotechnology Research Institute
FundersNational Science and Technology Major ProjectChina Agricultural Research SystemMinistry of Agriculture and Rural Affairs of the People's Republic of ChinaTaishan Scholar Project of Shandong ProvinceCentral Public-interest Scientific Institution Basal Research Fund, Chinese Academy of Fishery SciencesNatural Science Foundation of Shandong ProvinceNational Key Research and Development Program of ChinaChinese Academy of Agricultural SciencesNatural Science Foundation of Hebei ProvinceNational Natural Science Foundation of China
KeywordsProteomeComputational biologyBiologyCell biologyBioinformatics

Abstract

fetched live from OpenAlex

The soybean is a critical source of vegetable protein, but its proteome remains undercharacterized. Here, we quantify 12,855 proteins across 14 soybean organs using 4D data-independent acquisition mass spectrometry (4D-DIA-MS), creating the most extensive soybean proteome dataset to date. Organ-specific protein expression and co-expression analyses highlight functional specificity with significant differences in protein-transcript abundance across organs. We also map N 6 -methyladenosine (m 6 A) modifications, identifying their key role in post-transcriptional protein regulation. Integrative analysis of the proteome and m 6 A methylome identifies a novel regulator in m 6 A methylation. This comprehensive proteomic and m 6 A landscape advances our understanding of soybean biology and provides a valuable resource for crop improvement.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.206
Teacher spread0.202 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes1
Has abstractyes

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