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Record W4412111189 · doi:10.1093/dote/doaf050

The potential utility of CHATGPT4.0 as an AI assistant in the education and management of patients with Barrett’s esophagus

2025· article· en· W4412111189 on OpenAlexaff
Frances Dang, Joshua Kwon, Andy Lin, Shoujit Banerjee, Trevor McCracken, Amirali Tavangar, Shravani Reddy, Alyssa Y. Choi, Jennifer Phan, Jeffrey D. Mosko, Samir C. Grover, Tyler M. Berzin, Jason Samarasena

Bibliographic record

VenueDiseases of the Esophagus · 2025
Typearticle
Languageen
FieldMedicine
TopicEsophageal Cancer Research and Treatment
Canadian institutionsSt. Michael's Hospital
Fundersnot available
KeywordsMedicineEmpathyLikert scaleFamily medicineCLARITYConcordanceEosinophilic esophagitisInternal medicineDiseasePsychiatryPsychology

Abstract

fetched live from OpenAlex

Chat Generative Pre-trained Transformer (ChatGPT) has emerged as a new technology for physicians and patients to obtain medical information. Our aim was to assess the ability of ChatGPT 4.0 to deliver high-quality information in response to commonly asked questions and management recommendations for Barrett's esophagus (BE). Twenty-nine questions (14 clinical vignettes and 15 frequently asked questions (FAQ)) on BE were entered into ChatGPT 4.0. Using a 5-point Likert scale, three gastroenterologists with expertise in BE rated the 29 ChatGPT responses for accuracy, completeness, empathy, use of excessive medical jargon, and appropriateness to send to patients. Three separate gastroenterologists generated responses to the same 15 FAQs on BE. A group of blinded patients with BE evaluated both ChatGPT and gastroenterologist responses on quality, clarity, empathy and which of the two responses was preferred. Gastroenterologists rated ChatGPT responses as mostly accurate overall (4.01 out of 5) with 79.3% of responses completely accurate or mostly accurate with minor errors. When compared to gastroenterologist responses, the patient panel rated ChatGPT responses to be of significantly higher quality (4.42 vs. 3.07 out of 5) and empathy (4.33 vs. 2.55 out of 5) (p < 0.0001). In conclusion, ChatGPT 4.0 provides generally accurate and comprehensive information about BE. Patients expressed a clear preference for ChatGPT responses over those of gastroenterologists, finding responses from ChatGPT to be of higher quality and empathy. This study highlights the potential use of ChatGPT 4.0 as an adjunctive tool for physicians to provide real-time, high-quality information about BE to their patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.255
Threshold uncertainty score0.241

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.295
Teacher spread0.290 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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