MétaCan
Menu
Back to cohort
Record W4412135411 · doi:10.1177/21925682251359536

Extent of Fatty Infiltration of Lumbar Paraspinal Muscles as a Proxy for Frailty and Its Relationship with Perioperative Outcomes in Patients Undergoing Elective Spinal Surgery

2025· article· en· W4412135411 on OpenAlexaff
Ronit Kulkarni, Chase Walton, C. D'Amico, Melanie Bertolino, Jason Silvestre, Gabriella Rivas, Stephen J. Lewis, Christopher J. Nielsen, John A. Glaser, Charles A. Reitman, James P. Lawrence, Robert Ravinsky

Bibliographic record

VenueGlobal Spine Journal · 2025
Typearticle
Languageen
FieldMedicine
TopicHip and Femur Fractures
Canadian institutionsToronto Western HospitalUniversity of TorontoUniversity Health Network
Fundersnot available
KeywordsMedicinePerioperativeLumbarSpinal surgerySurgeryPhysical therapy

Abstract

fetched live from OpenAlex

Study DesignRetrospective Cohort Study.ObjectivesThe purpose of this study was to identify the role of lumbar paraspinal muscle fatty infiltration using the Goutallier classification in predicting perioperative outcomes following elective lumbar surgery.MethodsA retrospective review was conducted on patients who underwent elective one- or two-level lumbar decompressions or instrumented fusions for degenerative pathology at a single institution over a 3 year period. Patients were stratified by procedure type. Data included demographics, perioperative outcomes, and the 5-item Modified Frailty Index (MFI-5). Fatty infiltration was graded at L4-5 using the Goutallier classification (intraclass correlation coefficient = 0.908). Opportunistic osteoporosis screening used computed tomography-based Hounsfield units (HU) at L1-2. The relationships between Goutallier grade, demographics, MFI-5 score, and postoperative outcomes were analyzed using Chi-squared analyses, Fisher's exact test, Analysis of Variance, and multivariable logistic and linear regression.ResultsIn total, 314 patients met the inclusion criteria. Mean age was 68.9 ± 8.6 years; mean Goutallier score was 2.2 ± 1.1 and MFI-5 was 1.3 ± 1.0. Goutallier score significantly correlated with age, American Society of Anesthesiologists grade, steroid use, MFI-5, discharge disposition, and 180 day complications and reoperation. Subgroup analyses revealed differing associations between Goutallier score and comorbidities/outcomes across procedure types. Multivariable regression confirmed Goutallier score as predictive of 180 day complications, reoperation, non-home discharge, and frailty.ConclusionGoutallier score is a predictive marker of frailty and postoperative outcomes in lumbar spine surgery. Goutallier classification is an effective tool that can aid in risk stratification for patients undergoing lumbar spinal surgery.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.402

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.327
Teacher spread0.306 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueGlobal Spine JournalSame topicHip and Femur FracturesFrench-language works237,207