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Record W4412151422 · doi:10.1186/s12874-025-02616-z

A framework for clinical care pathway renewal: an example from inflammatory bowel disease

2025· article· en· W4412151422 on OpenAlexafffund
Kaitlyn Delaney Chappell, Lily Olayinka, Reed T. Sutton, Cynthia H. Seow, Jennifer deBruyn, Sander van Zanten, Christopher Ma, Brendan P. Halloran, Levinus A. Dieleman, K Wong, Remo Panaccione, Karen I. Kroeker

Bibliographic record

VenueBMC Medical Research Methodology · 2025
Typearticle
Languageen
FieldMedicine
TopicClinical practice guidelines implementation
Canadian institutionsAlberta Health ServicesAlberta HealthUniversity of CalgaryUniversity of Alberta
FundersCrohn's and Colitis CanadaUniversity of AlbertaAlberta Health Services
KeywordsInflammatory bowel diseaseMedicineIntensive care medicineInflammatory Bowel DiseasesMEDLINEDiseaseInternal medicinePolitical science

Abstract

fetched live from OpenAlex

BACKGROUND: Clinical care pathways (CCPs) contribute to standardized, high-quality care and reduce variation in healthcare delivery. However, CCPs must be regularly reviewed and updated to reflect current evidence-based clinical practice guidelines. In the literature, the development and implementation of CCPs is well described, but there is little to guide the process for renewal of CCPs as new evidence becomes available. METHODS: We sought to develop a recurrent framework for CCP renewal and apply this to provincial established CCPs for inflammatory bowel disease (IBD). The proposed framework was guided by a review matrix stratified based on two factors: risk to change and clinical impact of the CCPs. An in-person CCP workshop was conducted to facilitate advisor engagement, establish consensus on the review process, and apply the review matrix to existing IBD CCPs. Attendees, including gastroenterologists, nurses, pharmacists, colorectal surgeons, and a family physician, were invited to offer feedback on the proposed framework and vote on the definitions associated with each level of the matrix. They then applied the framework to existing CCPs in two voting rounds. RESULTS: A proposed framework for CCP renewal was drafted by a multidisciplinary leadership group and presented to 22 IBD stakeholders at the in-person workshop. After a discussion, attendees agreed the matrix should include four levels, based on either high or low risk to change and high or low clinical impact. Risk to change was defined as how quickly new evidence would evolve and render the CCP out of date, and clinical impact was defined as how important the CCP is to quality IBD care. Using the revised review matrix, the attendees were able to reach agreement regarding the level to be assigned to each existing CCP. CONCLUSIONS: The framework, based on risk to change and clinical impact is a valuable starting point to standardize the process of updating and renewing clinical pathways. Revising CCPs using our proposed framework ensures pathways are up-to-date and available to assist healthcare professionals in clinical decision-making. This framework can be adapted and customized to suit CCPs across healthcare disciplines and to facilitate the establishment of a renewal process.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.056
metaresearch head score (Gemma)0.649
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Insufficient payload (model declined to judge)
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.609
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0560.649
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.878
GPT teacher head0.720
Teacher spread0.158 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designOther design
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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