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Record W4412164949 · doi:10.1371/journal.pone.0326761

A behaviour change intervention promoting physical activity following dysvascular amputation: Protocol for a pilot study

2025· article· en· W4412164949 on OpenAlexaff
Crystal MacKay, Diana Zidarov, Brian Y. Chan, Steven Dilkas, Sander L. Hitzig, Andresa R. Marinho-Buzelli, Amanda L. Mayo, Michael W. Payne, Amy Schneeberg, Julia O. Totosy de Zepetnek, Dalton L. Wolfe, José Zariffa, Audrey Zucker-Levin, Susan Jaglal, Brittany Pousett, Heather Underwood, William C. Miller

Bibliographic record

VenuePLoS ONE · 2025
Typearticle
Languageen
FieldMedicine
TopicDiabetic Foot Ulcer Assessment and Management
Canadian institutionsGF Strong Rehabilitation CentreLondon Health Sciences CentreLawson Health Research InstituteUniversity of ReginaUniversity of British ColumbiaUniversity Health NetworkHealth Sciences CentreSunnybrook Health Science CentreWest Park Healthcare CentreUniversity of SaskatchewanUniversité de MontréalWestern UniversityUniversity of TorontoCentre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-MontréalCentre for Interdisciplinary Research in RehabilitationQueen's University
Fundersnot available
KeywordsProtocol (science)MedicineAmputationPhysical therapyPhysical activityIntervention (counseling)Physical medicine and rehabilitationAlternative medicineSurgeryNursingPathology

Abstract

fetched live from OpenAlex

BACKGROUND: Diabetes-related lower limb amputation (LLA) is a leading cause of disability globally, impacting individuals' physical and mental health, and ultimately their quality of life. Physical activity can reduce risk of chronic disease and mortality while improving quality of life. However, people with LLA often have reduced balance and walking ability resulting in sedentary behaviour. We co-created a physical activity intervention, IMproving Physical Activity through Coaching and Technology following Lower Limb Loss (IMPACT-L3), to support physical activity behaviour change in people with dysvasular LLA. To date, no studies have assessed a peer-led physical activity behaviour change intervention for people with LLA. Prior to launching a large trial, a pilot study is required to assess feasibility and optimize design of a future trial. METHODS: This pilot study is a parallel group randomized controlled trial (RCT) with an embedded qualitative component. The intervention group will have access to once-weekly virtual peer coaching sessions with a peer trained in brief action planning; web-based physical activity modules; and a wearable activity monitor for 8 weeks. The control group will continue usual care and be offered the intervention at the end of the follow-up period. Data on feasibility will be collected including assessment of process, resource, management and treatment indicators. The proposed primary outcomes will be measured at baseline, post-intervention and one month later: total physical activity counts per day measured by the ActiGraphTM activity monitor and self-efficacy measured by the Self-efficacy for Exercise scale. Secondary measures include patient reported outcome measures of physical activity, mobility, depression, social participation, balance confidence and quality of life. Semi-structured interviews will explore feasibility and acceptability of the intervention to participants and peers. DISCUSSION: This study will inform the design of a definitive RCT to determine the effectiveness of a peer-led physical activity intervention for people with dysvascular LLA.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.038
metaresearch head score (Gemma)0.027
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.085
Threshold uncertainty score0.284

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0380.027
Meta-epidemiology (narrow)0.0040.003
Meta-epidemiology (broad)0.0070.005
Bibliometrics0.0020.002
Science and technology studies0.0050.003
Scholarly communication0.0030.003
Open science0.0040.003
Research integrity0.0060.009
Insufficient payload (model declined to judge)0.0850.016

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.133
GPT teacher head0.392
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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Same venuePLoS ONESame topicDiabetic Foot Ulcer Assessment and ManagementFrench-language works237,207