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Record W4412190343 · doi:10.61093/hem.2025.2-01

Unlocking the Potential of Artificial Intelligence in Pharma Research and Development: Insights from Investor and Researcher Perspectives

2025· article· en· W4412190343 on OpenAlexaff
Jacob Kritikos, Andreas Sarantopoulos, Anastasios Roumeliotis, Julia Vasiliades, Ioannis Matsinas

Bibliographic record

VenueHealth Economics and Management Review · 2025
Typearticle
Languageen
FieldEngineering
TopicBiomedical and Engineering Education
Canadian institutionsCentre for Global Health Research
Fundersnot available
KeywordsManagement scienceEngineering ethicsPsychologyBusinessData scienceComputer scienceEngineering

Abstract

fetched live from OpenAlex

The integration of artificial intelligence into drug discovery processes represents a major innovation in pharmaceutical research and development. This study investigates the role of AI investments in enhancing research efficiency, addressing implementation challenges, and shaping stakeholder perspectives. Via a structured explanatory research design, the study applies a quantitative methodology based on survey data collected from researchers, investors, and pharmaceutical executives across the USA and United Kingdom. The questionnaire examined respondents’ experiences with artificial intelligence tools, investment patterns, and perceived research outcomes. Statistical methods such as logistic regression and chi-square tests were employed to analyze correlations between investment strategies and research efficiency. Findings indicate that while artificial intelligence improves productivity – in predictive modeling and data analysis – barriers such as high infrastructure costs, inadequate training, and regulatory uncertainty persist. Notably, 70% of participants plan to increase AI investments within the next five years, and 80% regard artificial intelligence as essential or very important to the future of drug discovery. However, successful implementation appears to correlate with firm size and access to technical resources, suggesting disparities in AI readiness across the industry. Recommendations include expanding artificial intelligence training programs, strengthening infrastructure, and fostering closer collaboration between investors and researchers. Ethical considerations, including data privacy and regulatory compliance, are also emphasized. The pilot study provides foundational insights for a full-scale investigation and offers practical guidance for optimizing artificial intelligence integration in pharmaceutical research and development.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.071
metaresearch head score (Gemma)0.048
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.071
Threshold uncertainty score0.377

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0710.048
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0030.003
Science and technology studies0.0020.008
Scholarly communication0.0130.009
Open science0.0010.004
Research integrity0.0040.004
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.088
GPT teacher head0.358
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations11
Published2025
Admission routes1
Has abstractyes

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