MétaCan
Menu
Back to cohort
Record W4412203782 · doi:10.19083/tesis/684256

Ingesta dietética de flavonoides y la incidencia de demencia en adultos mayores de 45 años: una revisión sistemática

2025· dissertation· es· W4412203782 on OpenAlexaboutno aff
Anmary Domínguez, R. García

Bibliographic record

VenueUniversidad Peruana de Ciencias Aplicadas (UPC) · 2025
Typedissertation
Languagees
FieldHealth Professions
TopicHealth and Lifestyle Studies
Canadian institutionsnot available
Fundersnot available
KeywordsHumanitiesGerontologyMedicineArt

Abstract

fetched live from OpenAlex

Objetivo: Sistematizar la literatura que evalúa la asociación entre el consumo de flavonoides en la dieta y la incidencia de demencia en adultos mayores de 45 años. Métodos: Se realizó una revisión sistemática de 14 estudios de cohorte publicados hasta abril de 2022 en Embase, PubMed, Scopus y Scielo. Se incluyeron estudios que evaluaron la ingesta dietética de flavonoides mediante cuestionarios validados, con desenlaces como deterioro cognitivo, Alzheimer o Parkinson. Los estudios fueron evaluados con la escala Newcastle-Ottawa, obteniendo puntuaciones de 6 a 9 puntos. Resultados: De un total de 1,525 artículos, se incluyeron 14 estudios de cohorte que abarcaron a 170,846 participantes de entre 45 y 98 años. Los resultados establecieron asociaciones significativas entre un alto consumo de flavonoides, en particular flavonoles y antocianinas, y un menor riesgo de deterioro cognitivo y Alzheimer en dos estudios que presentaron una alta calidad metodológica. No obstante, la heterogeneidad en los métodos de evaluación y los sesgos asociados a los cuestionarios dietéticos dificultaron la comparabilidad. Asimismo, la falta de análisis de biomarcadores y la aplicación inconsistente de herramientas cognitivas podrían limitar la validez de los hallazgos. Conclusión: Los flavonoides podrían tener un efecto protector frente a la demencia, aunque las limitaciones metodológicas actuales dificultan la obtención de conclusiones definitivas. Se sugiere que investigaciones futuras empleen diseños más homogéneos, incluyan biomarcadores y mejoren el control de factores confusores para fortalecer la base de evidencia.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.036
metaresearch head score (Gemma)0.078
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.036
Threshold uncertainty score0.191

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0360.078
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0040.008
Bibliometrics0.0140.008
Science and technology studies0.0010.001
Scholarly communication0.0040.003
Open science0.0020.002
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.370
Teacher spread0.349 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueUniversidad Peruana de Ciencias Aplicadas (UPC)Same topicHealth and Lifestyle StudiesFrench-language works237,207