Cognitive Behavior Treatment for Child and Adolescent Obsessive-Compulsive Disorder (OCD): One Year Treatment Responder Outcomes from the Nordic Long-term OCD Treatment Study (NordLOTS)
Bibliographic record
Abstract
Background: Obsessive-compulsive Disorder (OCD) affects between 0.25% and 4% of children and adolescents.<br/>Around 40% of youth with OCD continue to meet criteria for OCD well into adulthood. Cognitive behavioral<br/>therapy (CBT) is the recommended first line treatment for pediatric OCD. Consistent with the available followup<br/>research on pediatric OCD, we expected treatment effects, for initial treatment responders, to last<br/>throughout the first year following acute treatment. Methods: This prospective follow-up study was a part of<br/>the Nordic Long-term OCD Treatment Study (NordLOTS) in which 177 responders to 14 weeks of manualized<br/>CBT in an open trial program were assessed six and twelve months after treatment termination. Treatment<br/>response was defined as a Children’s Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) total score < 16, and<br/>remission was defined as a CY-BOCS total score ≤10. Results: At one-year follow-up 155 (87.6%) of the original<br/>sample were available for assessment and 142 (91.6%) were still rated as responders. Of these 121 (78.1%)<br/>were in remission. Mixed effects analysis revealed that patients continued to show symptom reduction over<br/>the one year follow-up period (F[2, 313.15] = 11.230, p < 0.001). Twenty-eight patients relapsed (CY-BOCS ≥16)<br/>during the one-year follow-up where of 11 returned to responder status by the 12-month assessment point.<br/>Conclusion: Results of this follow-up study suggest that manualized CBT applied in community settings has<br/>durable effects for initial responders to treatment, and that patients continue to improve during the first year<br/>following acute treatment. Clinical trials registration information: Nordic Long-term Obsessive-Compulsive<br/>Disorder (OCD) Treatment Study; www.controlled-trials.com; ISRCTN66385119.<br/>Long-Term Effectiveness of Cognitive Behavioral Treatment (CBT) and Sertraline
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".