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Record W4412365785 · doi:10.1038/s41598-025-08173-1

The role of virtual reality-based cognitive training in enhancing motivation and cognitive functions in individuals with chronic stroke

2025· article· en· W4412365785 on OpenAlexaboutno aff
Maria Grazia Maggio, Lilla Bonanno, Amelia Rizzo, Martina Barbera, Alessandra Benenati, Federica Impellizzeri, Francesco Corallo, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò

Bibliographic record

VenueScientific Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicStroke Rehabilitation and Recovery
Canadian institutionsnot available
FundersMinistero della Salute
KeywordsCognitionMontreal Cognitive AssessmentCognitive rehabilitation therapyRehabilitationStroke (engine)AnxietyCognitive trainingRandomized controlled trialPhysical therapyPsychologyMedicineChronic strokePhysical medicine and rehabilitationClinical psychologyPsychiatryCognitive impairmentInternal medicine

Abstract

fetched live from OpenAlex

Stroke represents a major health challenge worldwide, often resulting in significant long-term disability that affects cognitive, motor, and emotional functions. Rehabilitation strategies that enhance patient motivation are crucial for improving outcomes. This randomized controlled trial investigated the impact of Virtual Reality Rehabilitation Systems (VRRS) compared to traditional cognitive training on motivation, cognitive recovery, and emotional state in post-stroke patients. Fifty-four adults with chronic stroke were randomized into two equal groups (27 participants per group). The experimental group received 24 sessions of Virtual Reality (VR) cognitive training, while the control group underwent 24 sessions of traditional cognitive rehabilitation. Motivation was assessed using the McClelland test, while cognitive and emotional states were evaluated using the Montreal Cognitive Assessment (MoCA) and Hamilton Rating Scales for Anxiety and Depression (HAM-A, HAM-D). The experimental group exhibited significant improvements in motivation, with marked increases in Achievement (T0: 68.41 ± 15.81, T1: 68.93 ± 15.80; p < 0.001) and Affiliation(T0: 60.67 ± 14.64, T1: 60.93 ± 15.59; p = 0.006) dimensions, alongside enhanced cognitive function (T0: 24.781 ± 1.89, T1: 26 (24.5-27); p = 0.001), reduced depressive (T0: 41 ± 2.32, T1: 6 (4-8); p = 0.003) and anxiety symptoms (T0: 4.26 ± 1.99, T1: 3.30 ± 1.94; p < 0.001). The Control Group showed significant differences only in MOCA (T0: 25 (23-26.5), T1: 25 (24-27); p < 0.001). Between-group analysis revealed no significant differences between the two groups. These findings underscore the potential of VR as a multifaceted tool to boost motivation, facilitate cognitive recovery, and improve emotional state, offering a comprehensive approach to post-stroke rehabilitation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.275
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2025
Admission routes1
Has abstractyes

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