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Record W4412436450 · doi:10.1016/j.hest.2025.07.003

Grading of acute spontaneous cerebral hemorrhage combined with gut dysfunction assessment as a novel and improved prognostic score

2025· article· en· W4412436450 on OpenAlexaff
Meiqi Li, Mengyu Yang, K. H. Fu, Yiwen Xu, Dianbo Qu, Nan Lin, Tianwen Huang

Bibliographic record

VenueBrain Hemorrhages · 2025
Typearticle
Languageen
FieldMedicine
TopicIntracerebral and Subarachnoid Hemorrhage Research
Canadian institutionsUniversity of Ottawa
FundersFujian Provincial Health Technology ProjectFujian Medical UniversityNatural Science Foundation of Fujian Province
KeywordsMedicineGrading (engineering)Internal medicineCardiologyBiology

Abstract

fetched live from OpenAlex

Objective This study aimed to identify independent predictive factors for 6-month outcomes in acute intracerebral hemorrhage (ICH) patients and to develop a novel prognostic model incorporating gut dysfunction duration. Methods This retrospective analysis included 245 ICH patients, comparing 157 with favorable outcomes and 88 with poor outcomes. Logistic regression was used to identify independent predictors. A new model (ID-ICH) was developed by incorporating gut dysfunction duration into the ICH Grading Scale (ICH-GS). The model’s performance was evaluated using the area under the receiver operating characteristic curve (AUC) and calibration analysis. Results The poor-outcome group was older, had higher ICH-GS and National Institutes of Health Stroke Scale (NIHSS) scores, and longer gut dysfunction duration. Prolonged gut dysfunction duration (OR = 1.239, P < 0.001) was identified as an independent predictor of poor outcomes. The ID-ICH model (AUC = 0.718) outperformed the conventional ICH-GS model (AUC = 0.628). Conclusions Prolonged gut dysfunction is an independent predictor of poor outcomes in ICH patients. The ID-ICH model improves prognostic accuracy and could assist in individualized management

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.281
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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