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Record W4412437105 · doi:10.1016/j.heliyon.2025.e43606

Incidence, indications, and outcomes of emergency peripartum hysterectomy in Africa: A systematic review and meta-analysis

2025· review· en· W4412437105 on OpenAlexaboutno aff
Mulat Ayele, Eyob Shitie Lake, Befkad Derese Tilahun, Abebaw Alamrew, Chalie Mulugeta, Esuyawukal Mislu, Tegene Atamenta Kitaw, Gizachew Yilak

Bibliographic record

VenueHeliyon · 2025
Typereview
Languageen
FieldMedicine
TopicMaternal and fetal healthcare
Canadian institutionsnot available
Fundersnot available
KeywordsMeta-analysisIncidence (geometry)MedicineHysterectomyObstetricsSystematic reviewGeneral surgeryMEDLINEGynecologySurgeryPolitical scienceInternal medicine

Abstract

fetched live from OpenAlex

Introduction Even though emergency peripartum hysterectomy is a lifesaving procedure for the various life threatening indications, its incidence is increasing resulting with various intra and post-operative maternal and perinatal complication. The incidence, indication and outcomes of emergency peripartum hysterectomy are the indicators of quality of maternal care and also vary in different African countries. Therefore this systematic review and meta-analysis aimed to assess the pooled incidence, indication and outcomes of emergency peripartum hysterectomy in Africa. Objective To assess the pooled incidence, indication and outcomes of emergency peripartum hysterectomy in Africa. Methods A comprehensive search was done in PubMed, Cochrane Library, Hinari, Google Scholar, CINAHL, and Scopus between November 10 and 20, 2024 using searching terms. The quality of the included studies was assessed using Newcastle-Ottawa Quality Assessment Scale. Random effect model were used to estimate the pooled incidence using Stata version 17. Higgins's I 2 statistics, subgroup analysis, and publication bias was done accordingly. Result This systematic review and meta-analysis included 25 studies with a total of 611,704 participants. The pooled incidence of emergency peripartum hysterectomy among delivered mothers in Africa was 2.12 per 1000 delivered women (95 % CI: 2.00–2.33), with a heterogeneity index of I 2 = 93.07 %, P = 0.00. A higher incidence of emergency peripartum hysterectomy was observed in West Africa (3.02 per 1000; 95 % CI: 2.47–3.58), and lower in South Africa (2.43 per 1000; 95 % CI: 0.54–4.32). The most common indications for emergency peripartum hysterectomy were uterine rupture (44.96 %; 95 % CI: 34.96–55.28), uterine atony (29 %; 95 % CI: 22.31–35.7), and placenta accreta spectrum (15.71 %; 95 % CI: 10.65–20.78). The most common outcomes of emergency peripartum hysterectomy were maternal mortality (8.19 %; 95 % CI: 6.81–9.57), perinatal mortality (50.59 %; 95 % CI: 38.9–62.28), maternal sepsis (18.87 %; 95 % CI: 16.61–21.21), maternal severe anemia (71.26 %; 95 % CI: 67.43–75.09), disseminated intravascular coagulopathy (8 %; 95 % CI: 3.59–14.01), and urinary tract injury (3.99 %; 95 % CI: 2.60–5.38). Conclusion The incidence of emergency peripartum hysterectomy in Africa was higher compared to developed countries. Uterine rupture, uterine atony and placental accreta spectrum were the most common indication for emergency peripartum hysterectomy respectively. The maternal and perinatal mortality and morbidity was higher in Africa. This is due to poor quality of intrapartum, intraoperative and post-operative care in Africa. Therefore, capacity building in evidence based practice among the professionals to give the quality maternal care is needed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.702
Threshold uncertainty score0.710

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0090.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.114
GPT teacher head0.409
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2025
Admission routes1
Has abstractyes

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