Patent Foramen Ovale Closure in a Patient With Ventricular Storm and Arrhythmogenic Right Ventricular Cardiomyopathy
Bibliographic record
Abstract
BACKGROUND: Arrhythmogenic right ventricular cardiomyopathy (ARVC) has late clinical manifestations of right heart dysfunction, chamber dilation, and ventricular dysrhythmias. Elevated right-sided pressure and cardiac remodeling can result in late presentation of right to left interatrial shunting. CASE SUMMARY: A 70-year-old man presented with ventricular tachycardia (VT) storm and significant hypoxemia. His dysrhythmia settled with a combination of antiarrhythmic agents and a stellate ganglion block. Given the persistence of hypoxemia, which is a potential contributing factor to VT, further echocardiographic investigation diagnosed a large patent foramen ovale (PFO). After optimization of medical therapy, right heart catheterization demonstrated normal pulmonary artery pressures, and successful PFO closure with an Amplatzer device was performed. DISCUSSION: Development of right-to-left shunting with progression of ARVC is a rare late-stage complication, and its association with ventricular dysthymia has not been previously reported in the literature. This is the first case to our knowledge of PFO closure in ARVC for VT storm. TAKE-HOME MESSAGES: In advanced ARVC, right-sided chamber remodeling can result in stretching of the interatrial septum, leading to right-to-left shunting, hypoxemia, and ventricular dysrhythmia. Percutaneous PFO closure can be helpful in the management of RV failure, hypoxemia, and dysrhythmia in select patients with ARVC.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.003 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.001 | 0.002 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.005 | 0.003 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".