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Record W4412488379 · doi:10.1038/s41598-025-08600-3

Handedness modulates emotion cognition interactions as revealed by ERPs and alpha oscillations

2025· article· en· W4412488379 on OpenAlexaff
Peng Fan, Kathryn J. M. Lambert, Reyhaneh Bakhtiari, Anthony Singhal

Bibliographic record

VenueScientific Reports · 2025
Typearticle
Languageen
FieldNeuroscience
TopicHemispheric Asymmetry in Neuroscience
Canadian institutionsUniversity of AlbertaWomen and Children’s Health Research Institute
Fundersnot available
KeywordsElectroencephalographyPsychologyOddball paradigmCognitionEvent-related potentialLateralization of brain functionCognitive psychologyBrain activity and meditationContingent negative variationAlpha (finance)AudiologyNeuroscienceDevelopmental psychology

Abstract

fetched live from OpenAlex

Emotion and cognition are interrelated lateralized brain functions, yet their interaction may vary with handedness due to differences in hemispheric specialization. We investigate how handedness modulates emotion-cognition interactions using electroencephalography/event-related potentials (EEG/ERPs) in healthy young adults. Participants completed a hemi-field emotional oddball task, where visually identical circles appeared in either the left or right visual field, and fearful or neutral distractors were shown centrally. Circles on the block-specific "frequent" side served as standard stimuli, while those on the opposite side were spatially defined oddball targets. Neural activity was recorded using a 256-channel EEG system. Fearful distractors elicited greater ERP amplitudes (P100, P300, LPP) and increased alpha oscillations, reflecting heightened emotional processing and attentional engagement. Right-handers showed more adaptive engagement, with post-fear alpha suppression and enhanced P300 and LPP amplitudes to targets in right parietal sites, indicating efficient attentional reallocation via right hemisphere mechanisms. In contrast, left-handers exhibited bilateral ERP responses to fear and sustained bilateral alpha activity during subsequent target processing, suggesting greater reliance on inhibitory control to manage emotional carryover, but with reduced attentional reengagement. These findings reveal distinct lateralized patterns of emotion-attention interactions based on handedness, offering new insights into brain asymmetry and informing personalized educational and clinical approaches.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.061
Threshold uncertainty score0.876

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.002
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.293
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes1
Has abstractyes

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