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Record W4412489530 · doi:10.1097/brs.0000000000005457

Preservation of Distal Mobile Segments Reduces Risk of Rod Breakage in Adult Spinal Deformity Surgery

2025· article· en· W4412489530 on OpenAlexaff
Javier Pizones, Alejandro Gómez-Rice, Lucía Moreno-Manzanaro, Susana Núñez-Pereira, Sleiman Haddad, Anika Pupak, Frank Kleinstueck, Francisco Javier Sánchez Pérez-Grueso, Ibrahim Obeid, Ahmet Alanay, Ferrán Pellisé

Bibliographic record

VenueSpine · 2025
Typearticle
Languageen
FieldMedicine
TopicScoliosis diagnosis and treatment
Canadian institutionsObject Research Systems (Canada)
Fundersnot available
KeywordsMedicineSurgeryUnivariate analysisSpinal fusionScoliosisRetrospective cohort studyCobb angleMultivariate analysisDeformityPelvic tiltPelvisRadiographyCoronal planeInternal medicineRadiology

Abstract

fetched live from OpenAlex

STUDY DESIGN: Retrospective multicenter observational study. OBJECTIVE: To analyze whether avoiding fusion to the pelvis and preserving distal mobile segments reduces the risk of rod breakage (RB) after adult spinal deformity (ASD) surgery. SUMMARY OF BACKGROUND DATA: RB is a major complication in ASD surgery, mostly associated with age, malalignment, and pelvic fixation. However, the impact of different lower instrumented vertebrae (LIV) possibilities as an independent risk factor remains unclear. METHODS: We included ASD patients (aged 50-75) who underwent fusion of more than six levels, with LIV at or below L4, and a minimum two-year follow-up. Patients were categorized into those who did or did not experience rod breakage. Univariate and multivariate regression analyses assessed biological, surgical, and radiographic risk factors, with particular focus on LIV as an independent variable. RESULTS: Among 642 patients, 84% were female, mean age 64 years, BMI of 26.3, and ASD Frailty Index (ASD-FI) of 0.44. LIV distribution was L4 (52), L5 (44), S1 (48), and Iliac (498). RB occurred in 17.3% (113 patients). Univariate analysis linked RB to various alignment (preoperative global alignment and pelvic retroversion) and surgical factors (blood loss, osteotomies, levels fused, the use of cages, higher one-year coronal Cobb angle, and lower implant density). However, multivariate analysis identified two independent risk factors: implant density (OR: 0.98; 95% CI: 0.97-0.99) and LIV (OR: 0.74; 95% CI: 0.02-0.312), with LIV being the strongest predictor. Notably, RB appearance was significantly lower in patients with LIV at L4 or L5 (2.1%, 2/96) compared with those with LIV at S1 or Iliac (20.3%, 111/546). CONCLUSIONS: Selecting the lowest instrumented vertebra at L4 or L5 in ASD surgery significantly reduces rod breakage risk compared with pelvic fixation, independent of other biological, surgical, and radiographic variables. Preserving distal mobile segments, when feasible, may help prevent rod failure.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.305
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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